EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.1.3.4 | NEM | isozyme PAP1 is sensitive to NEM, while isozyme PAP2 is not | Rattus norvegicus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
3.1.3.4 | cytosol | isozyme PAP2 | Rattus norvegicus | 5829 | - |
3.1.3.4 | microsome | PAP1 | Rattus norvegicus | - |
- |
3.1.3.4 | additional information | isozyme PAP1 is located in all subcellular compartments, alterations in isozymes content in different subcellular compartments during aging, comparison of subcellular distribution in adult and aged rat cerebellum, overview | Rattus norvegicus | - |
- |
3.1.4.4 | additional information | enzyme activity is identical in adult and aged nuclear fraction, increases by 25% from adult to aged cerebellum in mitochondrial-synaptosomal fraction, decreases by 18% from adult to aged cerebellum in the microsomal fraction and increases by 14% from adult to aged cerebellum in cytosolic fraction | Rattus norvegicus | - |
- |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
3.1.3.4 | Mg2+ | isozyme PAP1 | Rattus norvegicus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.3.4 | additional information | Rattus norvegicus | the enzyme activity is involved in generation of phosphatidic acid and diaclyglycerol implicated in signal transduction, and in aging, overview | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.1.3.4 | Rattus norvegicus | - |
- |
- |
3.1.4.4 | Rattus norvegicus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.1.3.4 | cerebellum | isozyme PAP1 in all subcellular fractions, isozyme PAP2 in cytosol | Rattus norvegicus | - |
3.1.4.4 | cerebellum | development of phospholipase D activity during ageing. Enzyme activity is identical in adult and aged nuclear fraction, increases by 25% from adult to aged cerebellum in mitochondrial-synaptosomal fraction, decreases by 18% from adult to aged cerebellum in the microsomal fraction and increases by 14% from adult to aged cerebellum in cytosolic fraction | Rattus norvegicus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.3.4 | additional information | the enzyme activity is involved in generation of phosphatidic acid and diaclyglycerol implicated in signal transduction, and in aging, overview | Rattus norvegicus | ? | - |
? | |
3.1.4.4 | phosphatidylcholine + H2O | - |
Rattus norvegicus | 1,2-diacylglycerophosphate + choline | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.1.3.4 | PAP | - |
Rattus norvegicus |
3.1.3.4 | phosphatidate phosphohydrolase | - |
Rattus norvegicus |
3.1.4.4 | PIP2-PLD | - |
Rattus norvegicus |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
3.1.3.4 | 37 | - |
assay at | Rattus norvegicus |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
3.1.3.4 | 6.5 | - |
assay at | Rattus norvegicus |