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Literature summary extracted from
- Genetic evidence identifying the true gluconeogenic fructose-1,6-bisphosphatase in Thermococcus kodakaraensis and other hyperthermophiles (2004), J. Bacteriol., 186, 5799-5807.
Application
| EC Number | Application | Comment | Organism |
|---|---|---|---|
| 3.1.3.11 | additional information | deletion mutants of the isoforms imp and fbp. Fbp null mutant cannot grow under gluconeogenetic conditions while glycolytic growth is unimpaired, disruption results in complete abolishment of intracellular enzymic activity. Endogenous imp gene cannot complement the defect of fbp disruption, and its disruption does not lead to any detectable phenotypic changes | Thermococcus kodakarensis |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.1.3.11 | Thermococcus kodakarensis | - |
isoforms imp, inositol monophosphatatase/fructose 1,6-bisphosphatase ortholog, and fbp | - |
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