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Literature summary extracted from

  • Fallarino, F.; Vacca, C.; Orabona, C.; Belladonna, M.L.; Bianchi, R.; Marshall, B.; Keskin, D.B.; Mellor, A.L.; Fioretti, M.C.; Grohmann, U.; Puccetti, P.
    Functional expression of indoleamine 2,3-dioxygenase by murine CD8 alpha(+) dendritic cells (2002), Int. Immunol., 14, 65-68.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.13.11.52 gamma-interferon
-
 Mus musculus
1.13.11.52 O2-
-
 Mus musculus

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.13.11.52 1-methyl-DL-tryptophan competitive inhibitor Mus musculus
1.13.11.52 NO
-
 Mus musculus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.13.11.52 dendrite
-
 Mus musculus 30425
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.13.11.52 D-tryptophan + O2 Mus musculus
-
 N-formyl-D-kynurenine
-
 ?
1.13.11.52 D-tryptophan + O2 Mus musculus DBA/2J
-
 N-formyl-D-kynurenine
-
 ?
1.13.11.52 L-tryptophan + O2 Mus musculus
-
 N-formyl-L-kynurenine
-
 ?
1.13.11.52 L-tryptophan + O2 Mus musculus DBA/2J
-
 N-formyl-L-kynurenine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.13.11.52 Mus musculus
-
 DBA/2J
-
1.13.11.52 Mus musculus DBA/2J
-
 DBA/2J
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.13.11.52 peritoneal macrophage
-
 Mus musculus
-
1.13.11.52 spleen dentritic cells Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.13.11.52 D-tryptophan + O2
-
 Mus musculus N-formyl-D-kynurenine
-
 ?
1.13.11.52 D-tryptophan + O2
-
 Mus musculus DBA/2J N-formyl-D-kynurenine
-
 ?
1.13.11.52 L-tryptophan + O2
-
 Mus musculus N-formyl-L-kynurenine
-
 ?
1.13.11.52 L-tryptophan + O2
-
 Mus musculus DBA/2J N-formyl-L-kynurenine
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.13.11.52 IDO
-
 Mus musculus