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Literature summary extracted from
- Tissue plasminogen activator is a potent activator of PDGF-CC (2004), EMBO J., 23, 3793-3802.
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 3.4.21.68 | - |
Mus musculus |
| 3.4.21.68 | expressed in COS-1 cells | Mus musculus |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.21.68 | AEBSF | protease inhibitor | Mus musculus |  |
| 3.4.21.68 | Aprotinin | - |
Mus musculus | |
| 3.4.21.68 | leupeptin | - |
Mus musculus | |
| 3.4.21.68 | tPA-STOP | a synthetic specific inhibitor to tissue plasminogen activator | Mus musculus | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.21.68 | plasminogen + H2O | Mus musculus | - |
plasmin + ? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.21.68 | Mus musculus | P11214 | - |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.21.68 | fibroblast | - |
Mus musculus | - |
| 3.4.21.68 | kidney | - |
Mus musculus | - |
| 3.4.21.68 | lung | - |
Mus musculus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.21.68 | plasminogen + H2O | - |
Mus musculus | plasmin + ? | - |
? | |
| 3.4.21.68 | platelet-derived growth factor C + H2O | - |
Mus musculus | ? | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.4.21.68 | Tissue plasminogen activator | - |
Mus musculus |
| 3.4.21.68 | tPA | - |
Mus musculus |
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Release 2023.1 (January 2023)
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