Any feedback?
Literature summary extracted from
- Elementorganic bisonium reversible inhibitors of different cholinesterases (2004), Dokl. Biochem. Biophys., 395, 99-103.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.1.1.7 | 1-(hydroxymethyl)-5-methyloctahydro-2H-quinolizinium | pKi-values and comparison with inhibitory effect on horse and Berrytheutis magister butyrylcholinesterase EC 3.1.1.8 | Homo sapiens |  |
| 3.1.1.7 | 1-methyl-3-(3-(methylamino)cyclohexyl)pyridinium | pKi-values and comparison with inhibitory effect on horse and Berrytheutis magister butyrylcholinesterase EC 3.1.1.8 | Homo sapiens | |
| 3.1.1.7 | 2-(6-oxo-7,11-diazatricyclo(7.3.1.0 2,7)tridec-11-yl)ethyl acetate | pKi-values and comparison with inhibitory effect on horse and Berrytheutis magister butyrylcholinesterase EC 3.1.1.8 | Homo sapiens | |
| 3.1.1.7 | 3,3'-((1,5-dioxopentane-1,5-diyl)bis(iminocyclohexane-3,1-diyl))bis(1-methylpyridinium) | pKi-values and comparison with inhibitory effect on horse and Berrytheutis magister butyrylcholinesterase EC 3.1.1.8 | Homo sapiens | |
| 3.1.1.7 | 3-(6-oxo-6-(8-oxooctahydro-2H-2,6-methanopyrido(1,2-a)(1,5)diazocin-3(4H)-yl)hexanoyl)decahydro-8H-1,5-methanopyrido(1,2-a)(1,5)diazocin-8-one | pKi-values and comparison with inhibitory effect on horse and Berrytheutis magister butyrylcholinesterase EC 3.1.1.8 | Homo sapiens | |
| 3.1.1.7 | 7-methyloctahydro-2H-quinolizin-1-yl (7-methyloctahydro-2H-quinolizin-1-yl)methyl butanedioate | pKi-values and comparison with inhibitory effect on horse and Berrytheutis magister butyrylcholinesterase EC 3.1.1.8 | Homo sapiens | |
| 3.1.1.7 | N,N'-bis(3-pyridin-3-ylcyclohexyl)pentanediamide | pKi-values and comparison with inhibitory effect on horse and Berrytheutis magister butyrylcholinesterase EC 3.1.1.8 | Homo sapiens | |
| 3.1.1.7 | N,N,N,N',N',N'-hexamethylbutane-1,4-diaminium | pKi-values and comparison with inhibitory effect on horse and Berrytheutis magister butyrylcholinesterase EC 3.1.1.8 | Homo sapiens | |
| 3.1.1.7 | N,N,N-trimethylmethanaminium | pKi-values and comparison with inhibitory effect on horse and Berrytheutis magister butyrylcholinesterase EC 3.1.1.8 | Homo sapiens | |
| 3.1.1.7 | N-methyl-3-pyridin-3-ylcyclohexanamine | pKi-values and comparison with inhibitory effect on horse and Berrytheutis magister butyrylcholinesterase EC 3.1.1.8 | Homo sapiens | |
| 3.1.1.7 | octahydro-2H-quinolizin-1-yl octahydro-2H-quinolizin-1-ylmethyl butanedioate | pKi-values and comparison with inhibitory effect on horse and Berrytheutis magister butyrylcholinesterase EC 3.1.1.8 | Homo sapiens | |
| 3.1.1.7 | octahydro-2H-quinolizin-1-ylmethanol | pKi-values and comparison with inhibitory effect on horse and Berrytheutis magister butyrylcholinesterase EC 3.1.1.8 | Homo sapiens | |
| 3.1.1.8 | 1-(hydroxymethyl)-5-methyloctahydro-2H-quinolizinium | pKi-values and comparison with inhibitory effect on human acetylcholinesterase EC 3.1.1.7 and horse butyrylcholinesterase EC3.1.1.8 | Berryteuthis magister | |
| 3.1.1.8 | 1-(hydroxymethyl)-5-methyloctahydro-2H-quinolizinium | pKi-values and comparison with inhibitory effect on human acetylcholinesterase EC 3.1.1.7 and Berrytheutis magister butyrylcholinesterase EC 3.1.1.8 | Equus caballus | |
| 3.1.1.8 | 1-methyl-3-(3-(methylamino)cyclohexyl)pyridinium | pKi-values and comparison with inhibitory effect on human acetylcholinesterase EC 3.1.1.7 and horse butyrylcholinesterase EC3.1.1.8 | Berryteuthis magister | |
| 3.1.1.8 | 1-methyl-3-(3-(methylamino)cyclohexyl)pyridinium | pKi-values and comparison with inhibitory effect on human acetylcholinesterase EC 3.1.1.7 and Berrytheutis magister butyrylcholinesterase EC 3.1.1.8 | Equus caballus | |
| 3.1.1.8 | 2-(6-oxo-7,11-diazatricyclo(7.3.1.0 2,7)tridec-11-yl)ethyl acetate | pKi-values and comparison with inhibitory effect on human acetylcholinesterase EC 3.1.1.7 and horse butyrylcholinesterase EC3.1.1.8 | Berryteuthis magister | |
| 3.1.1.8 | 2-(6-oxo-7,11-diazatricyclo(7.3.1.0 2,7)tridec-11-yl)ethyl acetate | pKi-values and comparison with inhibitory effect on human acetylcholinesterase EC 3.1.1.7 and Berrytheutis magister butyrylcholinesterase EC 3.1.1.8 | Equus caballus | |
| 3.1.1.8 | 3,3'-((1,5-dioxopentane-1,5-diyl)bis(iminocyclohexane-3,1-diyl))bis(1-methylpyridinium) | pKi-values and comparison with inhibitory effect on human acetylcholinesterase EC 3.1.1.7 and horse butyrylcholinesterase EC3.1.1.8 | Berryteuthis magister | |
| 3.1.1.8 | 3,3'-((1,5-dioxopentane-1,5-diyl)bis(iminocyclohexane-3,1-diyl))bis(1-methylpyridinium) | pKi-values and comparison with inhibitory effect on human acetylcholinesterase EC 3.1.1.7 and Berrytheutis magister butyrylcholinesterase EC 3.1.1.8 | Equus caballus | |
| 3.1.1.8 | 3-(6-oxo-6-(8-oxooctahydro-2H-2,6-methanopyrido(1,2-a)(1,5)diazocin-3(4H)-yl)hexanoyl)decahydro-8H-1,5-methanopyrido(1,2-a)(1,5)diazocin-8-one | pKi-values and comparison with inhibitory effect on human acetylcholinesterase EC 3.1.1.7 and horse butyrylcholinesterase EC3.1.1.8 | Berryteuthis magister | |
| 3.1.1.8 | 3-(6-oxo-6-(8-oxooctahydro-2H-2,6-methanopyrido(1,2-a)(1,5)diazocin-3(4H)-yl)hexanoyl)decahydro-8H-1,5-methanopyrido(1,2-a)(1,5)diazocin-8-one | pKi-values and comparison with inhibitory effect on human acetylcholinesterase EC 3.1.1.7 and Berrytheutis magister butyrylcholinesterase EC 3.1.1.8 | Equus caballus | |
| 3.1.1.8 | 7-methyloctahydro-2H-quinolizin-1-yl (7-methyloctahydro-2H-quinolizin-1-yl)methyl butanedioate | pKi-values and comparison with inhibitory effect on human acetylcholinesterase EC 3.1.1.7 and horse butyrylcholinesterase EC3.1.1.8 | Berryteuthis magister | |
| 3.1.1.8 | 7-methyloctahydro-2H-quinolizin-1-yl (7-methyloctahydro-2H-quinolizin-1-yl)methyl butanedioate | pKi-values and comparison with inhibitory effect on human acetylcholinesterase EC 3.1.1.7 and Berrytheutis magister butyrylcholinesterase EC 3.1.1.8 | Equus caballus | |
| 3.1.1.8 | N,N'-bis(3-pyridin-3-ylcyclohexyl)pentanediamide | pKi-values and comparison with inhibitory effect on human acetylcholinesterase EC 3.1.1.7 and horse butyrylcholinesterase EC3.1.1.8 | Berryteuthis magister | |
| 3.1.1.8 | N,N'-bis(3-pyridin-3-ylcyclohexyl)pentanediamide | pKi-values and comparison with inhibitory effect on human acetylcholinesterase EC 3.1.1.7 and Berrytheutis magister butyrylcholinesterase EC 3.1.1.8 | Equus caballus | |
| 3.1.1.8 | N,N,N,N',N',N'-hexamethylbutane-1,4-diaminium | pKi-values and comparison with inhibitory effect on human acetylcholinesterase EC 3.1.1.7 and horse butyrylcholinesterase EC3.1.1.8 | Berryteuthis magister | |
| 3.1.1.8 | N,N,N,N',N',N'-hexamethylbutane-1,4-diaminium | pKi-values and comparison with inhibitory effect on human acetylcholinesterase EC 3.1.1.7 and Berrytheutis magister butyrylcholinesterase EC 3.1.1.8 | Equus caballus | |
| 3.1.1.8 | N,N,N-trimethylmethanaminium | pKi-values and comparison with inhibitory effect on human acetylcholinesterase EC 3.1.1.7 and horse butyrylcholinesterase EC3.1.1.8 | Berryteuthis magister | |
| 3.1.1.8 | N,N,N-trimethylmethanaminium | pKi-values and comparison with inhibitory effect on human acetylcholinesterase EC 3.1.1.7 and Berrytheutis magister butyrylcholinesterase EC 3.1.1.8 | Equus caballus | |
| 3.1.1.8 | N-methyl-3-pyridin-3-ylcyclohexanamine | pKi-values and comparison with inhibitory effect on human acetylcholinesterase EC 3.1.1.7 and horse butyrylcholinesterase EC3.1.1.8 | Berryteuthis magister | |
| 3.1.1.8 | N-methyl-3-pyridin-3-ylcyclohexanamine | pKi-values and comparison with inhibitory effect on human acetylcholinesterase EC 3.1.1.7 and Berrytheutis magister butyrylcholinesterase EC 3.1.1.8 | Equus caballus | |
| 3.1.1.8 | octahydro-2H-quinolizin-1-yl octahydro-2H-quinolizin-1-ylmethyl butanedioate | pKi-values and comparison with inhibitory effect on human acetylcholinesterase EC 3.1.1.7 and horse butyrylcholinesterase EC3.1.1.8 | Berryteuthis magister | |
| 3.1.1.8 | octahydro-2H-quinolizin-1-yl octahydro-2H-quinolizin-1-ylmethyl butanedioate | pKi-values and comparison with inhibitory effect on human acetylcholinesterase EC 3.1.1.7 and Berrytheutis magister butyrylcholinesterase EC 3.1.1.8 | Equus caballus | |
| 3.1.1.8 | octahydro-2H-quinolizin-1-ylmethanol | pKi-values and comparison with inhibitory effect on human acetylcholinesterase EC 3.1.1.7 and horse butyrylcholinesterase EC3.1.1.8 | Berryteuthis magister | |
| 3.1.1.8 | octahydro-2H-quinolizin-1-ylmethanol | pKi-values and comparison with inhibitory effect on human acetylcholinesterase EC 3.1.1.7 and Berrytheutis magister butyrylcholinesterase EC 3.1.1.8 | Equus caballus | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.1.1.7 | Homo sapiens | - |
- |
- |
| 3.1.1.8 | Berryteuthis magister | - |
- |
- |
| 3.1.1.8 | Equus caballus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.1.1.7 | serum | - |
Homo sapiens | - |
| 3.1.1.8 | ganglion | optical ganglion | Berryteuthis magister | - |
| 3.1.1.8 | serum | - |
Equus caballus | - |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
