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Literature summary extracted from

  • Fujihara, J.; Hieda, Y.; Xue, Y.; Nakagami, N.; Imamura, S.; Takayama, K.; Kataoka, K.; Takeshita, H.
    Actin-inhibition and folding of vertebrate deoxyribonuclease I are affected by mutations at residues 67 and 114 (2006), Comp. Biochem. Physiol. B, 143, 70-75.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.1.21.1 expression in COS-7 cells Xenopus laevis
3.1.21.1 expression in COS-7 cells Gloydius blomhoffii
3.1.21.1 expression in COS-7 cells Elaphe quadrivirgata
3.1.21.1 expression in COS-7 cells Homo sapiens
3.1.21.1 expression in COS-7 cells Sus scrofa

Protein Variants

EC Number Protein Variants Comment Organism
3.1.21.1 F114A protein is not expressed Xenopus laevis
3.1.21.1 F114A protein is not expressed Gloydius blomhoffii
3.1.21.1 F114A protein is not expressed Elaphe quadrivirgata
3.1.21.1 I67V inhibition by gamma-actin Elaphe quadrivirgata
3.1.21.1 S114A inhibition by gamma-actin Sus scrofa
3.1.21.1 S114F no inhibition by gamma-actin Sus scrofa
3.1.21.1 V67I no inhibition by g-actin Gloydius blomhoffii

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.21.1 gamma-actin
-
 Gloydius blomhoffii
3.1.21.1 gamma-actin
-
 Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.1.21.1 Elaphe quadrivirgata
-
-
-
3.1.21.1 Gloydius blomhoffii
-
-
-
3.1.21.1 Homo sapiens P24855
-
-
3.1.21.1 Sus scrofa P11936
-
-
3.1.21.1 Xenopus laevis
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.21.1 cell culture
-
 Xenopus laevis
-
3.1.21.1 cell culture
-
 Gloydius blomhoffii
-
3.1.21.1 cell culture
-
 Elaphe quadrivirgata
-
3.1.21.1 cell culture
-
 Homo sapiens
-
3.1.21.1 cell culture
-
 Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.21.1 double-stranded DNA + H2O
-
 Xenopus laevis ?
-
 ?
3.1.21.1 double-stranded DNA + H2O
-
 Gloydius blomhoffii ?
-
 ?
3.1.21.1 double-stranded DNA + H2O
-
 Elaphe quadrivirgata ?
-
 ?
3.1.21.1 double-stranded DNA + H2O
-
 Homo sapiens ?
-
 ?
3.1.21.1 double-stranded DNA + H2O
-
 Sus scrofa ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.21.1 deoxyribonuclease I
-
 Xenopus laevis
3.1.21.1 deoxyribonuclease I
-
 Gloydius blomhoffii
3.1.21.1 deoxyribonuclease I
-
 Elaphe quadrivirgata
3.1.21.1 deoxyribonuclease I
-
 Homo sapiens
3.1.21.1 deoxyribonuclease I
-
 Sus scrofa
3.1.21.1 DNase I
-
 Xenopus laevis
3.1.21.1 DNase I
-
 Gloydius blomhoffii
3.1.21.1 DNase I
-
 Elaphe quadrivirgata
3.1.21.1 DNase I
-
 Homo sapiens
3.1.21.1 DNase I
-
 Sus scrofa