EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.2.1.48 | valienamine | an aminocyclitol, isolated from the enzymolysis broth of validamycins, configuration is similar to alpha-D-glucose, IC50 in vitro is 1.17 mM, the inhibition is pH-dependent and competitive, 80% inhibition at 2.5 mM and pH 6.6 | Sus scrofa |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.2.1.48 | sucrose + H2O | Sus scrofa | - |
alpha-D-glucose + D-fructose | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.2.1.48 | Sus scrofa | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
3.2.1.48 | partially from intestinal mucosa by ammonium sulfate precipitation | Sus scrofa |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.2.1.48 | intestinal mucosa | - |
Sus scrofa | - |
3.2.1.48 | small intestine | - |
Sus scrofa | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
3.2.1.48 | additional information | - |
- |
Sus scrofa |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.2.1.48 | sucrose + H2O | - |
Sus scrofa | alpha-D-glucose + D-fructose | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.2.1.48 | sucrase | - |
Sus scrofa |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
3.2.1.48 | 37 | - |
assay at | Sus scrofa |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
3.2.1.48 | 6.6 | - |
- |
Sus scrofa |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.2.1.48 | 0.77 | - |
valienamine | pH 6.6, 37°C | Sus scrofa |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
3.2.1.48 | 1.17 | - |
an aminocyclitol, isolated from the enzymolysis broth of validamycins, configuration is similar to alpha-D-glucose, IC50 in vitro is 1.17 mM, the inhibition is pH-dependent and competitive, 80% inhibition at 2.5 mM and pH 6.6 | Sus scrofa | valienamine |