EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
3.2.1.18 | dithiothreitol | activates | Trypanosoma vivax | |
3.2.1.18 | dithiothreitol | 1 mM, activates 2fold | Trypanosoma vivax |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.2.1.18 | (6R)-5-amino-2,6-anhydro-3,5-dideoxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]-L-threo-hex-2-enonic acid | competitive | Trypanosoma vivax | |
3.2.1.18 | 2-deoxy-2,3 didehydro-N-acetyl-neuraminic acid | - |
Trypanosoma vivax | |
3.2.1.18 | N-bromosuccinimide | - |
Trypanosoma vivax | |
3.2.1.18 | p-hydroxy oxamic acid | - |
Trypanosoma vivax | |
3.2.1.18 | p-hydroxymercuribenzoate | 0.001 mM, complete inhibition | Trypanosoma vivax | |
3.2.1.18 | p-hydroxyoxamic acid | competitive | Trypanosoma vivax |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.2.1.18 | 0.17 | - |
Neu5Ac(alpha2,3)-lactose | pH 6.5, 37°C | Trypanosoma vivax | |
3.2.1.18 | 0.17 | - |
Neu5Ac(2-3)-alpha-lactose | 37°C, pH 6.7 | Trypanosoma vivax | |
3.2.1.18 | 0.45 | - |
fetuin | pH 6.5, 37°C | Trypanosoma vivax | |
3.2.1.18 | 0.45 | - |
fetuin | 37°C, pH 6.7 | Trypanosoma vivax |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
3.2.1.18 | Cu2+ | complete inhibition at 1 mM | Trypanosoma vivax | |
3.2.1.18 | Hg2+ | complete inhibition at 1 mM | Trypanosoma vivax |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
3.2.1.18 | 66000 | - |
gel filtration | Trypanosoma vivax |
3.2.1.18 | 68000 | - |
gel filtration | Trypanosoma vivax |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.2.1.18 | Trypanosoma vivax | - |
Agai strain | - |
3.2.1.18 | Trypanosoma vivax | - |
Agari strain | - |
3.2.1.18 | Trypanosoma vivax Agai | - |
Agai strain | - |
3.2.1.18 | Trypanosoma vivax Agari | - |
Agari strain | - |
EC Number | Posttranslational Modification | Comment | Organism |
---|---|---|---|
3.2.1.18 | glycoprotein | - |
Trypanosoma vivax |
EC Number | Purification (Comment) | Organism |
---|---|---|
3.2.1.18 | - |
Trypanosoma vivax |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.2.1.18 | bloodstream form | - |
Trypanosoma vivax | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
3.2.1.18 | 31 | - |
- |
Trypanosoma vivax |
3.2.1.18 | 31.02 | - |
- |
Trypanosoma vivax |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.2.1.18 | fetuin + H2O | - |
Trypanosoma vivax | ? | - |
? | |
3.2.1.18 | fetuin + H2O | - |
Trypanosoma vivax Agai | ? | - |
? | |
3.2.1.18 | fetuin + H2O | - |
Trypanosoma vivax Agari | ? | - |
? | |
3.2.1.18 | fetuin + H2O | - |
Trypanosoma vivax | Neu5Ac + ? | - |
? | |
3.2.1.18 | fetuin + H2O | - |
Trypanosoma vivax Agai | Neu5Ac + ? | - |
? | |
3.2.1.18 | fetuin + H2O | - |
Trypanosoma vivax Agari | Neu5Ac + ? | - |
? | |
3.2.1.18 | additional information | the enzyme is inactive towards Neu5,9Ac2(alpha2,6)-lactose, colomic acid and the gangliosides GM1, and GDI | Trypanosoma vivax | ? | - |
? | |
3.2.1.18 | additional information | the enzyme is inactive towards Neu5,9Ac2(alpha2,6)-lactose, colomic acid and the gangliosides GM1, and GDI | Trypanosoma vivax Agai | ? | - |
? | |
3.2.1.18 | additional information | the enzyme is inactive towards Neu5,9Ac2(alpha2,6)-lactose, colomic acid and the gangliosides GM1, and GDI | Trypanosoma vivax Agari | ? | - |
? | |
3.2.1.18 | Neu5Ac(2-3)-alpha-lactose + H2O | - |
Trypanosoma vivax | Neu5Ac + lactose | - |
? | |
3.2.1.18 | Neu5Ac(2-3)-alpha-lactose + H2O | - |
Trypanosoma vivax Agai | Neu5Ac + lactose | - |
? | |
3.2.1.18 | Neu5Ac(2-3)-alpha-lactose + H2O | - |
Trypanosoma vivax Agari | Neu5Ac + lactose | - |
? | |
3.2.1.18 | Neu5Ac(2-6)-alpha-lactose + H2O | - |
Trypanosoma vivax | Neu5Ac + lactose | - |
? | |
3.2.1.18 | Neu5Ac(2-6)-alpha-lactose + H2O | - |
Trypanosoma vivax Agai | Neu5Ac + lactose | - |
? | |
3.2.1.18 | Neu5Ac(2-6)-alpha-lactose + H2O | - |
Trypanosoma vivax Agari | Neu5Ac + lactose | - |
? | |
3.2.1.18 | Neu5Ac(alpha2,3)lactose + H2O | - |
Trypanosoma vivax | Neu5Ac + lactose | - |
? | |
3.2.1.18 | Neu5Ac(alpha2,6)-lactose + H2O | - |
Trypanosoma vivax | ? | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
3.2.1.18 | monomer | 1 * 66000, SDS-PAGE | Trypanosoma vivax |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
3.2.1.18 | 37 | - |
- |
Trypanosoma vivax |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
3.2.1.18 | 6.5 | - |
- |
Trypanosoma vivax |
EC Number | pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|---|
3.2.1.18 | 4 | 8.5 | complete cessation of activity at pH 4 and 8.5 | Trypanosoma vivax |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.2.1.18 | 0.06 | - |
2-deoxy-2,3 didehydro-N-acetyl-neuraminic acid | - |
Trypanosoma vivax | |
3.2.1.18 | 0.06 | - |
(6R)-5-amino-2,6-anhydro-3,5-dideoxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]-L-threo-hex-2-enonic acid | pH 6.5, 37°C | Trypanosoma vivax | |
3.2.1.18 | 0.15 | - |
p-hydroxy oxamic acid | - |
Trypanosoma vivax | |
3.2.1.18 | 0.15 | - |
p-hydroxyoxamic acid | pH 6.5, 37°C | Trypanosoma vivax |