BRENDA - Enzyme Database show

Rpe65 is the retinoid isomerase in bovine retinal pigment epithelium

Jin, M.; Li, S.; Moghrabi, W.N.; Sun, H.; Travis, G.H.; Cell 122, 449-459 (2005)

Data extracted from this reference:

Cloned(Commentary)
EC Number
Commentary
Organism
3.1.1.64
expressed in in baculovirus-infected Sf9 cells and in several 293T cell lines
Bos taurus
Engineering
EC Number
Amino acid exchange
Commentary
Organism
3.1.1.64
C330Y
inactive
Bos taurus
3.1.1.64
Y368H
inactive
Bos taurus
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
3.1.1.64
Bos taurus
-
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
3.1.1.64
retinal pigment epithelium
-
Bos taurus
-
3.1.1.64
retinal pigment epithelium cell
-
Bos taurus
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.1.1.64
all-trans-retinyl ester + H2O
-
664542
Bos taurus
11-cis-retinol + a fatty acid
-
-
-
?
Cloned(Commentary) (protein specific)
EC Number
Commentary
Organism
3.1.1.64
expressed in in baculovirus-infected Sf9 cells and in several 293T cell lines
Bos taurus
Engineering (protein specific)
EC Number
Amino acid exchange
Commentary
Organism
3.1.1.64
C330Y
inactive
Bos taurus
3.1.1.64
Y368H
inactive
Bos taurus
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
3.1.1.64
retinal pigment epithelium
-
Bos taurus
-
3.1.1.64
retinal pigment epithelium cell
-
Bos taurus
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.1.1.64
all-trans-retinyl ester + H2O
-
664542
Bos taurus
11-cis-retinol + a fatty acid
-
-
-
?