EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
3.1.3.16 | arachidonic acid | causes loss of heat shock protein interaction and increases Ppp5 activity, the effect of arachidonic acid on Ppp5 is increased by Rho kinase inhibitor Y27632, which is not affecting alone | Homo sapiens | |
3.1.3.16 | HSP70 | heat shock protein, activation of Ppp5 by dissociation from Hsp70 | Homo sapiens | |
3.1.3.16 | Hsp90 | heat shock protein, activation of Ppp5 by dissociation from Hsp90 | Homo sapiens | |
3.1.3.16 | additional information | activation of Ppp involves translocation from the nucleus to the cytoplasm, activation mechanism, overview | Homo sapiens | |
3.1.3.16 | nocodazole | causes loss of heat shock protein interaction and increases Ppp5 activity | Homo sapiens |
EC Number | Cloned (Comment) | Organism |
---|---|---|
3.1.3.16 | expression of FLAG-tagged Ppp5 in HEK-293 cells | Homo sapiens |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
3.1.3.16 | cytoplasm | activation of Ppp involves translocation from the nucleus to the cytoplasm | Homo sapiens | 5737 | - |
3.1.3.16 | nucleus | activation of Ppp involves translocation from the nucleus to the cytoplasm | Homo sapiens | 5634 | - |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
3.1.3.16 | 130000 | - |
x * 45000-50000 + x * 130000, recombinant Ppp5, SDS-PAGE | Homo sapiens |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.1.3.16 | Homo sapiens | - |
- |
- |
EC Number | Posttranslational Modification | Comment | Organism |
---|---|---|---|
3.1.3.16 | proteolytic modification | - |
Homo sapiens |
EC Number | Purification (Comment) | Organism |
---|---|---|
3.1.3.16 | recombinant FLAG-tagged and/or HA-tagged Ppp5 from HEK-293 cells | Homo sapiens |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.1.3.16 | HEK-293 cell | - |
Homo sapiens | - |
3.1.3.16 | HeLa cell | - |
Homo sapiens | - |
3.1.3.16 | MCF-7 cell | - |
Homo sapiens | - |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
3.1.3.16 | ? | x * 45000-50000 + x * 130000, recombinant Ppp5, SDS-PAGE | Homo sapiens |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.1.3.16 | Ppp5 | - |
Homo sapiens |
3.1.3.16 | protein phosphatase 5 | - |
Homo sapiens |