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Literature summary extracted from

  • Waghray, A.; Wang, D.S.; McKinsey, D.; Hayes, R.L.; Wang, K.K.
    Molecular cloning and characterization of rat and human calpain-5 (2004), Biochem. Biophys. Res. Commun., 324, 46-51.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.4.22.B25
-
 Rattus norvegicus
3.4.22.B25
-
 Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.22.B25 MDL-28170 blocks calpain-5 processing Homo sapiens
3.4.22.B25 N-ethylmaleimide blocks calpain-5 processing Homo sapiens

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.4.22.B25 Ca2+ calpain-5 is processed or autolyzed in the presence of Ca2+ Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.22.B25 76000
-
 calculated from amino acid sequence Rattus norvegicus
3.4.22.B25 76000
-
 1 * 76000, SDS-PAGE Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.4.22.B25 Homo sapiens O15484
-
-
3.4.22.B25 Rattus norvegicus Q8R4C0
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.22.B25 brain strong expression Rattus norvegicus
-
3.4.22.B25 brain strong expression Homo sapiens
-
3.4.22.B25 cerebellum strong expression Homo sapiens
-
3.4.22.B25 colon strong expression Homo sapiens
-
3.4.22.B25 frontal lobe strong expression Homo sapiens
-
3.4.22.B25 heart weak expression Rattus norvegicus
-
3.4.22.B25 hypothalamus strong expression Homo sapiens
-
3.4.22.B25 kidney strong expression Rattus norvegicus
-
3.4.22.B25 lung strong expression Rattus norvegicus
-
3.4.22.B25 medulla oblongata strong expression Homo sapiens
-
3.4.22.B25 SH-SY5Y cell
-
 Homo sapiens
-
3.4.22.B25 testis strong expression Homo sapiens
-
3.4.22.B25 thalamus strong expression Homo sapiens
-

Subunits

EC Number Subunits Comment Organism
3.4.22.B25 monomer 1 * 76000, SDS-PAGE Homo sapiens

Synonyms

EC Number Synonyms Comment Organism
3.4.22.B25 calpain-5
-
 Rattus norvegicus
3.4.22.B25 calpain-5
-
 Homo sapiens

pI Value

EC Number Organism Comment pI Value Maximum pI Value
3.4.22.B25 Rattus norvegicus calculated from amino acid sequence
-
 7.6