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Literature summary extracted from
- Homologous and heterologous expression of RNase III from Lactococcus lactis (2004), Biochem. Biophys. Res. Commun., 323, 884-890.
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 3.1.26.3 | expression in Escherichia coli. The lactococcal enzyme is able to substitute for Escherichia coli RNase III not only in the rRNA processing, but also in the processing of mRNAs. The amount of lactococcal rnc transcript in an Escherichia coli D strain is 3.3fold higher than in the wild type strain, suggesting that the Escherichia coli RNase III triggers the degradation of the heterologous rnc mRNA | Lactococcus lactis |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.26.3 | double-stranded RNA + H2O | Lactococcus lactis | the enzyme is able to process rRNAs and to regulate the levels of polynucleotide phosphorylase | 5'-phosphooligonucleotides | - |
? |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.1.26.3 | Lactococcus lactis | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.26.3 | double-stranded RNA + H2O | - |
Lactococcus lactis | 5'-phosphooligonucleotides | - |
? | |
| 3.1.26.3 | double-stranded RNA + H2O | the enzyme is able to process rRNAs and to regulate the levels of polynucleotide phosphorylase | Lactococcus lactis | 5'-phosphooligonucleotides | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 3.1.26.3 | Lac-RNase III | - |
Lactococcus lactis |
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Release 2023.1 (January 2023)
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