EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.1.3.30 | (2S,3R)-3-Hydroxybutane-1,2,3-tricarboxylate | Aspergillus nidulans | one of the key enzymes of the methylcitrate cycle. Deletion mutants do not grow on propionate as sole carbon and energy source and are severely inhibited during growth on alternative carbon sources, when propionate is present. The strongest inhibitory effect is observed, when glycerol is the main carbon source, followed by glucose and acetate. In addition, asexual conidiation is strongly impaired in the presence of propionate | Pyruvate + succinate | - |
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EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.1.3.30 | Aspergillus nidulans | - |
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- |
EC Number | Purification (Comment) | Organism |
---|---|---|
4.1.3.30 | - |
Aspergillus nidulans |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.1.3.30 | (2S,3R)-3-Hydroxybutane-1,2,3-tricarboxylate | one of the key enzymes of the methylcitrate cycle. Deletion mutants do not grow on propionate as sole carbon and energy source and are severely inhibited during growth on alternative carbon sources, when propionate is present. The strongest inhibitory effect is observed, when glycerol is the main carbon source, followed by glucose and acetate. In addition, asexual conidiation is strongly impaired in the presence of propionate | Aspergillus nidulans | Pyruvate + succinate | - |
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4.1.3.30 | (2S,3R)-3-Hydroxybutane-1,2,3-tricarboxylate | the enzyme is highly specific for (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate | Aspergillus nidulans | Pyruvate + succinate | - |
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