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Literature summary extracted from

  • Davies, E.; Tsang, C.W.; Ghazali, A.R.; Harris, R.M.; Waring, R.H.
    Effects of culture with TNF-alpha, TGF-beta and insulin on sulphotransferase (SULT 1A1 and 1A3) activity in human colon and neuronal cell lines (2004), Toxicol. In Vitro, 18, 749-754.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.8.2.1 additional information Homo sapiens culture of HT-29 cells with TNF-alpha increases activity of SULT1A1, TGF-beta increases activity to a lesser extent, insulin also increases activity of SULT1A1. TNF-alpha, TNF-beta and insulin have little effect on activity of enzyme in neuronal cell line SK-N-SH ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.8.2.1 Homo sapiens
-
 enzyme form SULT1A1
-
2.8.2.1 Homo sapiens
-
 enzyme form SULT1A3
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.8.2.1 HT-29 cell culture with TNF-alpha increases activity of SULT1A1, TGF-beta increases activity to a lesser extent, insulin also increases activity of SULT1A1 Homo sapiens
-
2.8.2.1 HT-29 cell culture with TNF-alpha increases activity of SULT1A1, TGF-beta increases activity to a lesser extent, insulin does not increase activity of SULT1A3 Homo sapiens
-
2.8.2.1 HT-29 cell HT-29. Culture with TNF-alpha increases activity of SULT1A1, TGF-beta increases activity to a lesser extent, insulin also increases activity of SULT1A1 Homo sapiens
-
2.8.2.1 HT-29 cell HT-29. Culture with TNF-alpha increases activity of SULT1A1, TGF-beta increases activity to a lesser extent, insulin does not increase activity of SULT1A3 Homo sapiens
-
2.8.2.1 neuronal cell line SK-N-SH. TNF-alpha, TNF-beta and insulin have little effect in activity of enzyme form SULT1A3 Homo sapiens
-
2.8.2.1 neuronal cell line SK-N-SH. TNF-alpha, TNF-beta and insulin have little effect on activity of enzyme form SULT1A1 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.8.2.1 3'-phosphoadenylylsulfate + 4-nitrophenol enzyme form SULT1A1 Homo sapiens adenosine 3',5'-bisphosphate + 4-nitrophenyl sulfate
-
 ?
2.8.2.1 3'-phosphoadenylylsulfate + 4-nitrophenol enzyme form SULT1A3 Homo sapiens adenosine 3',5'-bisphosphate + 4-nitrophenyl sulfate
-
 ?
2.8.2.1 3'-phosphoadenylylsulfate + dopamine enzyme form SULT1A1 Homo sapiens adenosine 3',5'-bisphosphate + ?
-
 ?
2.8.2.1 3'-phosphoadenylylsulfate + dopamine enzyme form SULT1A3 Homo sapiens adenosine 3',5'-bisphosphate + ?
-
 ?
2.8.2.1 additional information culture of HT-29 cells with TNF-alpha increases activity of SULT1A1, TGF-beta increases activity to a lesser extent, insulin also increases activity of SULT1A1. TNF-alpha, TNF-beta and insulin have little effect on activity of enzyme in neuronal cell line SK-N-SH Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.8.2.1 SULT1A1
-
 Homo sapiens
2.8.2.1 SULT1A3
-
 Homo sapiens