EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
2.3.1.37 | additional information | linkage of two subunits into a single polypeptide chain dimer 2XALAS, results in enzyme with about 7fold greater turnover number than wild-type and with greater A410/A330 ratio | Mus musculus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.3.1.37 | 0.45 | - |
succinyl-CoA | pH 7.5, 30°C, mutant 2XALAS | Mus musculus | |
2.3.1.37 | 0.63 | - |
succinyl-CoA | pH 7.5, 20°C, mutant 2XALAS | Mus musculus | |
2.3.1.37 | 2 | 3 | glycine | pH 7.5, 30°C, wild-type | Mus musculus | |
2.3.1.37 | 2.3 | - |
succinyl-CoA | pH 7.5, 30°C, wild-type | Mus musculus | |
2.3.1.37 | 11 | - |
succinyl-CoA | pH 7.5, 20°C, wild-type | Mus musculus | |
2.3.1.37 | 11.7 | - |
glycine | pH 7.5, 20°C, mutant 2XALAS | Mus musculus | |
2.3.1.37 | 14 | - |
glycine | pH 7.5, 20°C, wild-type | Mus musculus | |
2.3.1.37 | 16.7 | - |
glycine | pH 7.5, 30°C, mutant 2XALAS | Mus musculus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.3.1.37 | Mus musculus | - |
erythroid specific isoform | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.1.37 | succinyl-CoA + glycine | - |
Mus musculus | 5-aminolevulinate + CoA + CO2 | - |
? |
EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.3.1.37 | 0.016 | - |
glycine | pH 7.5, 20°C, wild-type | Mus musculus | |
2.3.1.37 | 0.11 | - |
glycine | pH 7.5, 20°C, mutant 2XALAS | Mus musculus | |
2.3.1.37 | 0.167 | - |
glycine | pH 7.5, 30°C, wild-type | Mus musculus | |
2.3.1.37 | 0.92 | - |
glycine | pH 7.5, 30°C, mutant 2XALAS | Mus musculus |