EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
5.1.1.4 | extracellular | during infection of its mammalian host, the parasite secretes a proline racemase that contributes to parasite immune evasion by acting as a B-cell mitogen | Trypanosoma cruzi | - |
- |
5.1.1.4 | intracellular | TcPRACB secretes the intracellular isoform of the enzyme. TcPRACA gene can generate both secreted and intracellular isoforms (by an alternative trans-splicing mechanism) | Trypanosoma cruzi | 5622 | - |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
5.1.1.4 | L-Pro | Trypanosoma cruzi | overexpression of TcPRAC leads to an increase in parasite differentiation into infective forms and its subsequent penetration into host cells. During infection of its mammalian host, the parasite secretes a proline racemase that contributes to parasite immune evasion by acting as a B-cell mitogen | D-Pro | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
5.1.1.4 | Trypanosoma cruzi | Q4DA80 | - |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
5.1.1.4 | L-Pro | overexpression of TcPRAC leads to an increase in parasite differentiation into infective forms and its subsequent penetration into host cells. During infection of its mammalian host, the parasite secretes a proline racemase that contributes to parasite immune evasion by acting as a B-cell mitogen | Trypanosoma cruzi | D-Pro | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
5.1.1.4 | TcPRAC | - |
Trypanosoma cruzi |
5.1.1.4 | TcPRACA | - |
Trypanosoma cruzi |
5.1.1.4 | TcPRACB | - |
Trypanosoma cruzi |