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Literature summary extracted from

  • Perez-Villasenor, G.; Tovar, A.R.; Moranchel, A.H.; Hernandez-Pando, R.; Hutson, S.M.; Torres, N.
    Mitochondrial branched chain aminotransferase gene expression in AS-30D hepatoma rat cells and during liver regeneration after partial hepatectomy in rat (2005), Life Sci., 78, 334-339.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.6.1.42 1
-
 L-leucine mitochondria of AS-30D cell, pH 7.8, 37°C Rattus norvegicus
2.6.1.42 1.3
-
 L-isoleucine mitochondria of AS-30D cell, pH 7.8, 37°C Rattus norvegicus
2.6.1.42 2.1
-
 L-valine mitochondria of AS-30D cell, pH 7.8, 37°C Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.6.1.42 41000
-
 x * 41000, SDS-PAGE Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
2.6.1.42 Rattus norvegicus
-
 mitochondrial isoform
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
2.6.1.42 additional information enzyme activity is associated with an immunoreactive band of 41000 Da, and an immunoreactive band of 43000 Da corresponds to inactive enzyme Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.6.1.42 AS-30D cell hepatoma cell, expresses only mitochondrial isoform Rattus norvegicus
-
2.6.1.42 liver regenerating liver after partial hepatectomy, enzyme activity between day 3 and 6 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.6.1.42 7
-
 regenerating liver, pH 7.8, 37°C Rattus norvegicus
2.6.1.42 18.6
-
 mitochondria of AS-30D cell, pH 7.8, 37°C Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.6.1.42 L-isoleucine + 2-oxoglutarate
-
 Rattus norvegicus 3-methyl-2-oxopentanoate + L-glutamate
-
 ?
2.6.1.42 L-leucine + 2-oxoglutarate
-
 Rattus norvegicus 2-oxoisohexanoate + L-glutamate
-
 ?
2.6.1.42 L-valine + 2-oxoglutarate
-
 Rattus norvegicus 2-oxoisopentanoate + L-glutamate
-
 ?

Subunits

EC Number Subunits Comment Organism
2.6.1.42 ? x * 41000, SDS-PAGE Rattus norvegicus