Literature summary extracted from

Chow, S.Y.; Williams, H.J.; Huang, Q.; Nanda, S.; Scott, A.I.
Studies on taxadiene synthase: interception of the cyclization cascade at the isocembrene stage with GGPP analogues (2005), J. Org. Chem., 70, 9997-10003.

Organism

EC Number	Organism	UniProt	Comment	Textmining
4.2.3.17	Taxus brevifolia	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
4.2.3.17	(10,11R)-dihydrogeranylgeranyl diphosphate	-	Taxus brevifolia	(1S,12R)-11,12-dihydroisocembrene + diphosphate	-	?
4.2.3.17	(10,11S)-dihydrogeranylgeranyl diphosphate	-	Taxus brevifolia	(1S,12S)-11,12-dihydroisocembrene + diphosphate	-	?
4.2.3.17	(2E,6E,10Z)-geranylgeranyl diphosphate	-	Taxus brevifolia	(1S,11,12Z)-isocembrene + diphosphate	-	?
4.2.3.17	11-desmethylgeranylgeranyl diphosphate	-	Taxus brevifolia	(1S)-12-desmethylisocembrene + diphosphate	-	?
4.2.3.17	geranylgeranyl diphosphate	isocembrenyl cation is possibly an intermediate in the cyclization of geranylgeranyl diphosphate to taxadiene	Taxus brevifolia	taxa-4,11-diene + diphosphate	-	?

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Release 2023.1 (January 2023)