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Literature summary extracted from

  • Laurila, M.R.; Salgado, P.S.; Stuart, D.I.; Grimes, J.M.; Bamford, D.H.
    Back-priming mode of phi6 RNA-dependent RNA polymerase (2005), J. Gen. Virol., 86, 521-526.
    View publication on PubMed

Organism

EC Number Organism UniProt Comment Textmining
2.7.7.48 Cystovirus phi6 P11124
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.7.48 nucleoside triphosphate + RNAn the polymerase structure is switchable, with a discrete set of contacts stabilizing the initiation-competent form of the enzyme so that relatively modest changes can have-range effects, controlling the switch from the initiation to elongation phase, with premature conformational switching producing a structure that preferentially initiates by back-priming Cystovirus phi6 diphosphate + RNAn+1
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Synonyms

EC Number Synonyms Comment Organism
2.7.7.48 RNA-dependent RNA polymerase
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Cystovirus phi6