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Literature summary extracted from

  • Kumar, P.; Koppisch, A.T.; Cane, D.E.; Khosla, C.
    Enhancing the modularity of the modular polyketide synthases: transacylation in modular polyketide synthases catalyzed by malonyl-CoA:ACP transacylase (2003), J. Am. Chem. Soc., 125, 14307-14312.
    View publication on PubMed

Application

EC Number Application Comment Organism
2.3.1.39 biotechnology the enzyme is active as part of a recombinant engineered modular enzyme complex system for modified and designed polyketid synthesis, overview Streptomyces coelicolor

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.3.1.39 expression in Escherichia coli strain BL21(DE3) Streptomyces coelicolor

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.39 malonyl-CoA + [acyl-carrier protein] Streptomyces coelicolor
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CoA + malonyl-[acyl-carrier protein]
-
?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.39 Streptomyces coelicolor
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.39 malonyl-CoA + [acyl-carrier protein]
-
Streptomyces coelicolor CoA + malonyl-[acyl-carrier protein]
-
?
2.3.1.39 malonyl-CoA + [acyl-carrier protein] enzyme is active with a type II [acyl-carrier protein] from a recombinant modular polyketid synthase with inactivated acyl transferase domain, overview Streptomyces coelicolor CoA + malonyl-[acyl-carrier protein]
-
?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.39 malonyl-CoA:ACP transacylase
-
Streptomyces coelicolor
2.3.1.39 MAT
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Streptomyces coelicolor