EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
6.3.1.20 | additional information | lipB mutant strain, grows well when supplemented with octanoate in place of lipoate | Escherichia coli |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
6.3.1.20 | additional information | Escherichia coli | LplA potein attaches octanoate to the dehydrogenase and LipA protein then converts the octanoate to lipoate | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.7.60 | Escherichia coli | - |
- |
- |
2.8.1.8 | Escherichia coli | - |
- |
- |
6.3.1.20 | Escherichia coli | - |
- |
- |
6.3.1.20 | Escherichia coli | - |
isoenzymes LipB, LplA | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.7.60 | additional information | lipoate-protein ligase attaches octanoate to the dehydrogenase subunit and sulfur insertion protein LipA then converts octanoate to lipoate. LipA acts on both octanoate and octanoyl-proteins | Escherichia coli | ? | - |
? | |
2.8.1.8 | protein N6-(octanoyl)lysine + sulfur + S-adenosyl-L-methionine | octanoylated pyruvate dehydrogenase E2 domain | Escherichia coli | protein N6-(lipoyl)lysine + 2 L-methionine + 5'-deoxyadenosyl radical | - |
? | |
6.3.1.20 | ATP + octanoate + pyruvate dehydrogenase subunit E2 | lipoate-protein ligase attaches octanoate to the dehydrogenase subunit and sulfur insertion protein LipA, then converts octanoate to lipoate. LipA acts on both octanoate and octanoyl-proteins | Escherichia coli | diphosphate + AMP + octanoyl-pyruvate dehydrogenase subunit E2 | - |
? | |
6.3.1.20 | additional information | LplA potein attaches octanoate to the dehydrogenase and LipA protein then converts the octanoate to lipoate | Escherichia coli | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.7.7.60 | LipA | - |
Escherichia coli |
6.3.1.20 | LPLA | - |
Escherichia coli |