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Literature summary extracted from

  • Nelson, K.; Melville, E.L.; Meikle, P.J.; Anson, D.S.
    Immortalisation of a mucopolysaccharidosis type IIIC fibroblast cell line via expression of SV40 T antigen (2003), Cell Biol. Int., 27, 567-570.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.3.1.78 cytogenetic analysis of skin fibroblast cell lines derived from enzyme-deficient mutant parent cell line and immortalized cell lines Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.78 lysosomal membrane transmembrane enzyme Homo sapiens 5765
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.78 additional information Homo sapiens enzyme deficiency causes mucopolysaccharidosis type IIIC ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.78 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.78 partially, preparation of lysosomal membranes Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.78 cell culture from primary skin fibroblasts, wild-type SF4528 and KD8, and MPS IIIC mutants thereof Homo sapiens
-
2.3.1.78 additional information immortalization of cell lines, the cells retain the mucopolysaccharidosis type IIIC phenotype, overview Homo sapiens
-
2.3.1.78 skin fibroblast
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.78 acetyl-CoA + phosphatidylethanolamine
-
 Homo sapiens CoA + N-acetylphosphatidylethanolamine
-
 ?
2.3.1.78 additional information enzyme deficiency causes mucopolysaccharidosis type IIIC Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.78 GNAT
-
 Homo sapiens

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.3.1.78 37
-
 assay at Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.1.78 7
-
 assay at Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
2.3.1.78 acetyl-CoA
-
 Homo sapiens