Literature summary extracted from

Lin, H.; Vadali, R.V.; Bennett, G.N.; San, K.Y.
Increasing the acetyl-CoA pool in the presence of overexpressed phosphoenolpyruvate carboxylase or pyruvate carboxylase enhances succinate production in Escherichia coli (2004), Biotechnol. Prog., 20, 1599-1604.

Activating Compound

EC Number	Activating Compound	Comment	Organism	Structure
6.4.1.1	acetyl-CoA	-	Lactococcus lactis

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
4.1.1.49	increasing the acetyl-CoA pool in the presence of overexpressed phosphoenolpyruvate carboxylase enhances succinate production in Escherichia coli	Sorghum sp.
6.4.1.1	expression in Escherichia coli GJT001, coexpression with pantothenate kinase	Lactococcus lactis

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
6.4.1.1	ATP + pyruvate + HCO3-	Lactococcus lactis	-	ADP + oxaloacetate + phosphate	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
4.1.1.49	Sorghum sp.	-	-	-
6.4.1.1	Lactococcus lactis	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
6.4.1.1	ATP + pyruvate + HCO3-	-	Lactococcus lactis	ADP + oxaloacetate + phosphate	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
4.1.1.49	PEPC	-	Sorghum sp.
6.4.1.1	PYC	-	Lactococcus lactis

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)