Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Gerken, T.A.
    Kinetic modeling confirms the biosynthesis of mucin core 1 (beta-Gal(1-3) alpha-GalNAc-O-Ser/Thr) O-glycan structures are modulated by neighboring glycosylation effects (2004), Biochemistry, 43, 4137-4142.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.1.122 additional information
-
 additional information kinetic modeling, numerical simulation of in vivo Core 1 glycosylation pattern Sus scrofa

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.1.122 UDP-galactose + glycoprotein N-acetyl-D-galactosamine Sus scrofa the enzyme can O-glycosylate the mucin-like domains of glycoproteins in a site-specific manner dependent on the sort of glycosylation/presence of glycan C-terminal from site of action, a position specific glycosylation pattern results, regulation, overview UDP + glycoprotein D-galactosyl-1,3-N-acetyl-D-galactosamine
-
 ?
2.4.1.122 UDP-galactose + salivary gland mucin 81 N-acetyl-D-galactosamine Sus scrofa glycosylation pattern of the mucin, overview UDP + salivary gland mucin 81 D-galactosyl-1,3-N-acetyl-D-galactosamine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.122 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.122 salivary gland
-
 Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.122 UDP-galactose + glycoprotein N-acetyl-D-galactosamine
-
 Sus scrofa UDP + glycoprotein D-galactosyl-1,3-N-acetyl-D-galactosamine
-
 ?
2.4.1.122 UDP-galactose + glycoprotein N-acetyl-D-galactosamine the enzyme can O-glycosylate the mucin-like domains of glycoproteins in a site-specific manner dependent on the sort of glycosylation/presence of glycan C-terminal from site of action, a position specific glycosylation pattern results, regulation, overview Sus scrofa UDP + glycoprotein D-galactosyl-1,3-N-acetyl-D-galactosamine
-
 ?
2.4.1.122 UDP-galactose + salivary gland mucin 81 N-acetyl-D-galactosamine
-
 Sus scrofa UDP + salivary gland mucin 81 D-galactosyl-1,3-N-acetyl-D-galactosamine
-
 ?
2.4.1.122 UDP-galactose + salivary gland mucin 81 N-acetyl-D-galactosamine glycosylation pattern of the mucin, overview Sus scrofa UDP + salivary gland mucin 81 D-galactosyl-1,3-N-acetyl-D-galactosamine
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.4.1.122 core 1 transferase
-
 Sus scrofa
2.4.1.122 UDP-galactose:glycoprotein-alpha-GalNAc beta3-galactosyltransferase
-
 Sus scrofa