BRENDA - Enzyme Database show

Regulation of the membrane-localized prostaglandin E synthases mPGES-1 and mPGES-2 in cardiac myocytes and fibroblasts

Giannico, G.; Mendez, M.; LaPointe, M.C.; Am. J. Physiol. 288, H165-H174 (2005)

Data extracted from this reference:

Activating Compound
EC Number
Activating Compound
Commentary
Organism
Structure
5.3.99.3
glutathione
-
Rattus norvegicus
Molecular Weight [Da]
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
5.3.99.3
16000
-
SDS-PAGE
Rattus norvegicus
5.3.99.3
33000
-
SDS-PAGE
Rattus norvegicus
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
5.3.99.3
Rattus norvegicus
-
Sprague-Dawley rat
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
5.3.99.3
cardiac myocyte
colocalized with cyclooxygenase-2
Rattus norvegicus
-
5.3.99.3
fibroblast
colocalized with cyclooxygenase-2
Rattus norvegicus
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
5.3.99.3
Prostaglandin H2
-
660677
Rattus norvegicus
Prostaglandin E2
-
-
-
?
Activating Compound (protein specific)
EC Number
Activating Compound
Commentary
Organism
Structure
5.3.99.3
glutathione
-
Rattus norvegicus
Molecular Weight [Da] (protein specific)
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
5.3.99.3
16000
-
SDS-PAGE
Rattus norvegicus
5.3.99.3
33000
-
SDS-PAGE
Rattus norvegicus
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
5.3.99.3
cardiac myocyte
colocalized with cyclooxygenase-2
Rattus norvegicus
-
5.3.99.3
fibroblast
colocalized with cyclooxygenase-2
Rattus norvegicus
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
5.3.99.3
Prostaglandin H2
-
660677
Rattus norvegicus
Prostaglandin E2
-
-
-
?