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Literature summary extracted from

  • Graves, P.R.; Kwiek, J.J.; Fadden, P.; et al.
    Discovery of novel targets of quinoline drugs in the human purine binding proteome (2002), Mol. Pharmacol., 62, 1364-1372.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.10.5.1 Chloroquine
-
 Homo sapiens
1.10.5.1 mefloquine
-
 Homo sapiens
1.10.5.1 primaquine
-
 Homo sapiens
1.10.5.1 Quinacrine
-
 Homo sapiens
1.10.5.1 Quinine
-
 Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
1.10.5.1 Homo sapiens
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.10.5.1 N-methyldihydronicotinamide + menadione
-
 Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.10.5.1 QR2
-
 Homo sapiens
1.10.5.1 quinone reductase 2
-
 Homo sapiens

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
1.10.5.1 0.00051
-
 Quinacrine
-
 Homo sapiens
1.10.5.1 0.00061
-
 Chloroquine
-
 Homo sapiens
1.10.5.1 0.00104
-
 primaquine
-
 Homo sapiens
1.10.5.1 0.017
-
 mefloquine
-
 Homo sapiens
1.10.5.1 0.252
-
 Quinine
-
 Homo sapiens