EC Number | Cloned (Comment) | Organism |
---|---|---|
1.8.3.2 | gene cpQSOx1, primary gene sequence, DNA and amino acid sequence analysis, stable expression of the wild-type enzyme in MCF-7 cells with intra- and extracellular localization of the recombinant enzyme, expression of the His-tagged enzyme in Escherichia coli strain BL21(DE3) | Cavia porcellus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
1.8.3.2 | extracellular | enzyme is secreted | Cavia porcellus | - |
- |
1.8.3.2 | perikaryon | - |
Cavia porcellus | 43204 | - |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
1.8.3.2 | 68000 | - |
x * 68000, recombinant His-tagged enzyme, SDS-PAGE | Cavia porcellus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.8.3.2 | R-SH + O2 | Cavia porcellus | enzyme plays a role in synaptic strengthening and in redox activities in the brain | R-S-S-R + H2O2 | - |
ir |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.8.3.2 | Cavia porcellus | O08841 | - |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
1.8.3.2 | recombinant His-tagged enzyme from Escherichia coli strain BL21(DE3) by nickel chelate chromatography | Cavia porcellus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.8.3.2 | basal forebrain | - |
Cavia porcellus | - |
1.8.3.2 | brain | detailed tissue distribution analysis in brain, overview | Cavia porcellus | - |
1.8.3.2 | brain stem | - |
Cavia porcellus | - |
1.8.3.2 | central nervous system | highest enzyme expression in reticular structures, such as the basal forebrain, reticular thalamic nucleus, and reticular nuclei of the brainstem | Cavia porcellus | - |
1.8.3.2 | endometrium | specific expression in glandular and luminal epithelial cells | Cavia porcellus | - |
1.8.3.2 | epithelium | secretory, endometrial | Cavia porcellus | - |
1.8.3.2 | lung | - |
Cavia porcellus | - |
1.8.3.2 | neuron | - |
Cavia porcellus | - |
1.8.3.2 | ovary | - |
Cavia porcellus | - |
1.8.3.2 | secretory cell | - |
Cavia porcellus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.8.3.2 | dithiothreitol + O2 | - |
Cavia porcellus | dithiothreitol disulfide + H2O2 | - |
ir | |
1.8.3.2 | R-SH + O2 | - |
Cavia porcellus | R-S-S-R + H2O2 | - |
ir | |
1.8.3.2 | R-SH + O2 | enzyme plays a role in synaptic strengthening and in redox activities in the brain | Cavia porcellus | R-S-S-R + H2O2 | - |
ir |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
1.8.3.2 | ? | x * 68000, recombinant His-tagged enzyme, SDS-PAGE | Cavia porcellus |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.8.3.2 | More | enzyme belongs to the sulfhydryl oxidase/Quiescin Q6 family | Cavia porcellus |
1.8.3.2 | QSOx1 | - |
Cavia porcellus |
1.8.3.2 | sulfhydryl oxidase | - |
Cavia porcellus |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
1.8.3.2 | 37 | - |
assay at | Cavia porcellus |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
1.8.3.2 | 8 | - |
assay at | Cavia porcellus |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.8.3.2 | FAD | dependent on | Cavia porcellus |