EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
1.6.2.4 | additional information | addition of trypsin significantly increases activity in detergent free buffer, no effect in the presence of detergent | Rhizopus stolonifer |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.6.2.4 | NADP+ | - |
Rhizopus stolonifer |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
1.6.2.4 | membrane | - |
Rhizopus stolonifer | 16020 | - |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
1.6.2.4 | 78000 | - |
SDS-PAGE, band is accompanied by two smaller, proteolytic forms of the enzyme formed during solubilization or purification | Rhizopus stolonifer |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.6.2.4 | 2 ferricytochrome P450 + NADPH | Rhizopus stolonifer | involved in the hydroxylation of progesterone at the 11alpha position | 2 ferrocytochrome P450 + NADP+ + H+ | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.6.2.4 | Rhizopus stolonifer | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
1.6.2.4 | - |
Rhizopus stolonifer |
EC Number | Reaction | Comment | Organism | Reaction ID |
---|---|---|---|---|
1.6.2.4 | NADPH + oxidized hemoprotein = NADP+ + reduced hemoprotein + H+ | at high ionic strength nonclassical two-site ping pong mechanism, at low ionic strength a sequential bisubstrate mechanism | Rhizopus stolonifer |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.6.2.4 | mycelium | - |
Rhizopus stolonifer | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.6.2.4 | 2 ferricytochrome c + NADPH | at high ionic strength nonclassical two-site ping pong mechanism, at low ionic strength a sequential bisubstrate mechanism | Rhizopus stolonifer | 2 ferrocytochrome c + NADP+ + H+ | - |
? | |
1.6.2.4 | 2 ferricytochrome P450 + NADPH | involved in the hydroxylation of progesterone at the 11alpha position | Rhizopus stolonifer | 2 ferrocytochrome P450 + NADP+ + H+ | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.6.2.4 | NADPH-cytochrome P450 reductase | - |
Rhizopus stolonifer |
1.6.2.4 | NADPH-ferrihemoprotein reductase | - |
Rhizopus stolonifer |
1.6.2.4 | NADPH:ferrihemoprotein oxidoreductase | - |
Rhizopus stolonifer |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.6.2.4 | FAD | together with FMN | Rhizopus stolonifer | |
1.6.2.4 | FMN | together with FAD | Rhizopus stolonifer | |
1.6.2.4 | NADPH | - |
Rhizopus stolonifer |