EC Number | Application | Comment | Organism |
---|---|---|---|
2.1.2.1 | medicine | enzyme is a target for antibiotics | Escherichia coli |
2.1.2.1 | medicine | the cytosolic SHMT is a target enzyme for chemotherapy | Homo sapiens |
EC Number | Cloned (Comment) | Organism |
---|---|---|
2.1.2.1 | - |
Homo sapiens |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.1.2.1 | cytosol | - |
Homo sapiens | 5829 | - |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.1.2.1 | additional information | Homo sapiens | the enzyme plays an indispensable role in nucleic acid biosynthesis | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.1.2.1 | Escherichia coli | - |
- |
- |
2.1.2.1 | Homo sapiens | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.1.2.1 | - |
Homo sapiens |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.1.2.1 | L-Ser + tetrahydrofolate | - |
Escherichia coli | Gly + 5,10-methylenetetrahydrofolate | - |
r | |
2.1.2.1 | L-Ser + tetrahydrofolate | - |
Homo sapiens | Gly + 5,10-methylenetetrahydrofolate | - |
r | |
2.1.2.1 | additional information | the enzyme plays an indispensable role in nucleic acid biosynthesis | Homo sapiens | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.1.2.1 | eSHMT | - |
Escherichia coli |
2.1.2.1 | hSHMT | - |
Homo sapiens |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
2.1.2.1 | pyridoxal 5'-phosphate | - |
Escherichia coli | |
2.1.2.1 | pyridoxal 5'-phosphate | - |
Homo sapiens |