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Literature summary extracted from

  • Torrents, E.; Poplawski, A.; Sjoberg, B.M.
    Two proteins mediate class II ribonucleotide reductase activity in Pseudomonas aeruginosa: expression and transcriptional analysis of the aerobic enzymes (2005), J. Biol. Chem., 280, 16571-16578.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.17.4.2 additional information Pseudomonas aeruginosa the two-component class II RNR is primarily used for DNA repair and/or possibly DNA replication at low oxygen tension. It can support bacterial growth in the absence of class I RNR activity ?
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?

Organism

EC Number Organism UniProt Comment Textmining
1.17.4.2 Pseudomonas aeruginosa
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-
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Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.17.4.2 additional information exponentialy grown cells predominantly express class I enzyme compared with class II enzyme, activity in stationary phase cells Pseudomonas aeruginosa
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.17.4.2 CTP + reduced thioredoxin
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Pseudomonas aeruginosa dCTP + thioredoxin disulfide + H2O
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?
1.17.4.2 additional information the two-component class II RNR is primarily used for DNA repair and/or possibly DNA replication at low oxygen tension. It can support bacterial growth in the absence of class I RNR activity Pseudomonas aeruginosa ?
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?

Subunits

EC Number Subunits Comment Organism
1.17.4.2 More the enzyme is encoded by two consecutive open reading frames denated nrdJa and nrdJb and separated by 16 bp. The presence of both NrdJa and NrdJb subunits is absolutely essential for enzyme activity Pseudomonas aeruginosa

Synonyms

EC Number Synonyms Comment Organism
1.17.4.2 class II RNR
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Pseudomonas aeruginosa