Literature summary extracted from

Fu, T.F.; Scarsdale, J.N.; Kazanina, G.; Schirch, V.; Wright, H.T.
Location of the pteroylpolyglutamate-binding site on rabbit cytosolic serine hydroxymethyltransferase (2003), J. Biol. Chem., 278, 2645-2653.

Crystallization (Commentary)

EC Number	Crystallization (Comment)	Organism
2.1.2.1	crystal structure at 2.7 A resolution of the recombinant enzyme with active-site bound 5-formyl-tetrahydropteroylglutamate is obtained by soaking unliganded crystals of of the recombinant enzyme in 5-formyl-tetrahydropteroylglutamate, the conformation of the pteridine ring and its interactions with the enzyme differ slightly from those observed in complexes of the monoglutamate cofactor	Oryctolagus cuniculus

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining
2.1.2.1	cytosol	-	Oryctolagus cuniculus	5829	-

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.1.2.1	Oryctolagus cuniculus	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.1.2.1	5,10-methylenetetrahydrofolate + glycine + H2O	-	Oryctolagus cuniculus	tetrahydrofolate + L-serine	-	r

Synonyms

EC Number	Synonyms	Comment	Organism
2.1.2.1	SHMT	-	Oryctolagus cuniculus

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Release 2023.1 (January 2023)