Literature summary extracted from

Gattis, S.G.; Palfey, B.A.
Direct observation of the participation of flavin in product formation by thyX-encoded thymidylate synthase (2005), J. Am. Chem. Soc., 127, 832-833.

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.1.1.148	Campylobacter jejuni	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.1.1.148	5,10-methylenetetrahydrofolate + dUMP + FADH2	the flavin is oxidized after dUMP reacts with 5,10-methylenetetrahydrofolate	Campylobacter jejuni	dTMP + tetrahydrofolate + FAD	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
2.1.1.148	thyX-encoded thymidylate synthase	-	Campylobacter jejuni

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
2.1.1.148	FAD	the flavin is oxidized after dUMP reacts with 5,10-methylenetetrahydrofolate	Campylobacter jejuni
2.1.1.148	FADH2	the flavin is oxidized after dUMP reacts with 5,10-methylenetetrahydrofolate	Campylobacter jejuni

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Release 2023.1 (January 2023)