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Literature summary extracted from

  • Wu, Y.W.; Lai, W.F.; Tsai, Y.H.
    Characterization of purified rat testicular transglutaminase and age-dependent changes of the enzyme activities (2005), Int. J. Biochem. Cell Biol., 37, 386-396.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.2.13 ATP 2 mM, 27% inhibition Rattus norvegicus
2.3.2.13 Ca2+ above 10 mM Rattus norvegicus
2.3.2.13 cadaverine 2 mM, 70% inhibition Rattus norvegicus
2.3.2.13 cystamine 2 mM, 58% inhibition Rattus norvegicus
2.3.2.13 EGTA 5 mM, 100% inhibition Rattus norvegicus
2.3.2.13 GTP 2 mM, 80% inhibition Rattus norvegicus
2.3.2.13 Monodansylcadaverine 2 mM, 97% inhibition Rattus norvegicus
2.3.2.13 NaCl 500 mM, 58% inhibition Rattus norvegicus
2.3.2.13 putrescine 2 mM, 75% inhibition Rattus norvegicus
2.3.2.13 spermidine 2 mM, 70% inhibition Rattus norvegicus
2.3.2.13 spermine 2 mM, 68% inhibition Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.2.13 0.017
-
 N,N-dimethylcasein pH 9.0, 37°C Rattus norvegicus
2.3.2.13 0.035
-
 putrescine pH 9.0, 37°C Rattus norvegicus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.3.2.13 Ca2+ optimal at 5-10 mM, inhibitory above 10 mM Rattus norvegicus
2.3.2.13 Mg2+ required for GTPase activity, but not for GPT binding Rattus norvegicus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.2.13 78000
-
 x * 78000, SDS-PAGE Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.2.13 additional information Rattus norvegicus enzyme is related with the first wave of spermatogenesis ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.2.13 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.2.13
-
 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.2.13 testis
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.2.13 additional information enzyme is related with the first wave of spermatogenesis Rattus norvegicus ?
-
 ?
2.3.2.13 putrescine + N,N'-dimethylcasein
-
 Rattus norvegicus ?
-
 ?

Subunits

EC Number Subunits Comment Organism
2.3.2.13 ? x * 78000, SDS-PAGE Rattus norvegicus