Literature summary extracted from
Prabhu, H.R.
In vivo inhibition of selenium dependent glutathione peroxidase and superoxide dismutase in rats by diethyldithiocarbamate (2002), Indian J. Exp. Biol., 40, 258-261.
Inhibitors
EC Number |
Inhibitors |
Comment |
Organism |
Structure |
---|
1.11.1.9 |
diethyldithiocarbamate |
significant inhibition of selenium-dependent enzyme after intraperitoneal injection of rats with diethyldithiocarbamate, which returns to normal at 48 h after administration of injection. It is possible that inhibition of superoxide dismutase by diethyldithiocarbamate leads to accumulation of superoxide anion which in turn inactivates selenium-dependent glutathione peroxidase by its reaction with slenium at the active site of the enzyme |
Rattus norvegicus |
|
Metals/Ions
EC Number |
Metals/Ions |
Comment |
Organism |
Structure |
---|
1.11.1.9 |
selenium |
selenium-dependent enzyme |
Rattus norvegicus |
|
Organism
EC Number |
Organism |
UniProt |
Comment |
Textmining |
---|
1.11.1.9 |
Rattus norvegicus |
- |
- |
- |
Source Tissue
EC Number |
Source Tissue |
Comment |
Organism |
Textmining |
---|