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Literature summary extracted from
- Differential expression of glutathione reductase and cytosolic glutathione peroxidase, GPX1, in developing rat lungs and kidneys (2002), Free Radic. Res., 36, 1041-1049.
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.8.1.7 | glutathione disulfide + NADPH | Rattus norvegicus | - |
glutathione + NADP+ | - |
? |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.8.1.7 | Rattus norvegicus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.8.1.7 | bronchiole | - |
Rattus norvegicus | - |
| 1.8.1.7 | bronchus | - |
Rattus norvegicus | - |
| 1.8.1.7 | epithelium | lung | Rattus norvegicus | - |
| 1.8.1.7 | kidney | tubule and cortex, developmental changes in enzyme activity from fetal prenatal over neonatal to adult stage, overview, gradual increase with maximum at adult age | Rattus norvegicus | - |
| 1.8.1.7 | lung | mainly in epithelium, low content in alveoli, developmental changes in enzyme activity from fetal prenatal over neonatal to adult stage, overview, substantially constant | Rattus norvegicus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.8.1.7 | glutathione disulfide + NADPH | - |
Rattus norvegicus | glutathione + NADP+ | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.8.1.7 | glutathione reductase | - |
Rattus norvegicus |
| 1.8.1.7 | GR | - |
Rattus norvegicus |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 1.8.1.7 | 30 | - |
assay at | Rattus norvegicus |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 1.8.1.7 | 7 | - |
assay at | Rattus norvegicus |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.8.1.7 | NADPH | - |
Rattus norvegicus | |
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Release 2023.1 (January 2023)
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