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Literature summary extracted from

  • He, J.; Roy, B.; Perigaud, C.; Kashlan, O.B.; Cooperman, B.S.
    The enantioselectivities of the active and allosteric sites of mammalian ribonucleotide reductase (2005), FEBS J., 272, 1236-1242.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.17.4.1 L-ADP inhibition of D-ADP reduction, competitive inhibition of dGTP-dependent D-ADP reductase Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
1.17.4.1 Mus musculus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.17.4.1 ADP + reduced thioredoxin
-
 Mus musculus 2'-dADP + thioredoxin disulfide + H2O
-
 ?
1.17.4.1 CDP + reduced thioredoxin
-
 Mus musculus 2'-dCDP + thioredoxin disulfide + H2O
-
 ?
1.17.4.1 additional information no substrate activity for L-ribofuranosyl-adenine 5'-diphosphate Mus musculus ?
-
 ?

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
1.17.4.1 1
-
 L-ADP
-
 Mus musculus