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Literature summary extracted from

  • Chen, C.J.; Huang, H.S.; Chang, W.C.
    Depletion of phospholipid hydroperoxide glutathione peroxidase up-regulates arachidonate metabolism by 12(S)-lipoxygenase and cyclooxygenase 1 in human epidermoid carcinoma A431 cells (2003), FASEB J., 17, 1694-1696.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.13.11.31 additional information Homo sapiens endogenous phospholipid hydroperoxide glutathione peroxidase plays a pivotal role in the regulation of 12(S)-lipoxygenase and cyclooxygenase 1 activities by reducing the level of intracellular lipid hydroperoxides in arachidonate metabolism in A431 cells ?
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 ?

Organism

EC Number Organism UniProt Comment Textmining
1.13.11.31 Homo sapiens
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-
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Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.13.11.31 A-431 cell
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 Homo sapiens
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.13.11.31 arachidonate + O2
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 Homo sapiens (5Z,8Z,10E,14Z)-(12S)-12-hydroperoxyicosa-5,8,10,14-tetraenoate
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 ?
1.13.11.31 additional information endogenous phospholipid hydroperoxide glutathione peroxidase plays a pivotal role in the regulation of 12(S)-lipoxygenase and cyclooxygenase 1 activities by reducing the level of intracellular lipid hydroperoxides in arachidonate metabolism in A431 cells Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.13.11.31 12(S)-lipoxygenase
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 Homo sapiens