EC Number | Cloned (Comment) | Organism |
---|---|---|
2.5.1.81 | expressed in Escherichia coli as a glutathione S-transferase fusion protein | Aeropyrum pernix |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.5.1.81 | (2E,6E)-farnesyl diphosphate + 2 isopentenyl diphosphate | Aeropyrum pernix | Aeropyrum pernix does not possess geranylgeranyl diphosphate synthase and has only C25-C25 ether lipids, but no C20-containing ether lipids. Aeropyrum pernix farnesylgeranyl diphosphate synthase is important in the biosynthesis of the hydrocarbon moiety of membrane lipids | (2E,6E,10E,14E)-geranylfarnesyl diphosphate + 2 diphosphate | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.5.1.81 | Aeropyrum pernix | Q9UWR6 | - |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.5.1.81 | - |
Aeropyrum pernix |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.5.1.81 | (2E,6E)-farnesyl diphosphate + 2 isopentenyl diphosphate | Aeropyrum pernix does not possess geranylgeranyl diphosphate synthase and has only C25-C25 ether lipids, but no C20-containing ether lipids. Aeropyrum pernix farnesylgeranyl diphosphate synthase is important in the biosynthesis of the hydrocarbon moiety of membrane lipids | Aeropyrum pernix | (2E,6E,10E,14E)-geranylfarnesyl diphosphate + 2 diphosphate | - |
? | |
2.5.1.81 | (2E,6E)-farnesyl diphosphate + 2 isopentenyl diphosphate | farnesyl diphosphate is the allylic substrate with the highest activity | Aeropyrum pernix | (2E,6E,10E,14E)-geranylfarnesyl diphosphate + 2 diphosphate | - |
? | |
2.5.1.81 | dimethylallyl diphosphate + 4 isopentenyl diphosphate | dimethylallyl diphosphate shows 28% of the activity with farnesyl diphosphate | Aeropyrum pernix | (2E,6E,10E,14E)-geranylfarnesyl diphosphate + 4 diphosphate | large amounts of intermediates are formed: geranyl diphosphate, farnesyl diphosphate, geranylgeranyl diphosphate | ? | |
2.5.1.81 | geranyl diphosphate + 3 isopentenyl diphosphate | geranyl diphosphate shows 72% of the activity with farnesyl diphosphate | Aeropyrum pernix | (2E,6E,10E,14E)-geranylfarnesyl diphosphate + 3 diphosphate | - |
? | |
2.5.1.81 | geranylgeranyl diphosphate + isopentenyl diphosphate | geranylgeranyl diphosphate shows 65% of the activity with farnesyl diphosphate | Aeropyrum pernix | (2E,6E,10E,14E)-geranylfarnesyl diphosphate + diphosphate | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.5.1.81 | C25 farnesylgeranyl diphosphate synthase | - |
- |
2.5.1.81 | farnesylgeranyl diphosphate synthase | - |
- |
2.5.1.81 | FGPP synthase | - |
Aeropyrum pernix |
2.5.1.81 | Fgs | - |
Aeropyrum pernix |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
2.5.1.81 | 7.5 | - |
assay at | Aeropyrum pernix |