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Literature summary extracted from

  • Virkel, G.; Lifschitz, A.; Sallovitz, J.; Pis, A.; Lanusse, C.
    Comparative hepatic and extrahepatic enantioselective sulfoxidation of albendazole and fenbendazole in sheep and cattle (2004), Drug Metab. Dispos., 32, 536-544.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.14.13.32 microsome
-
Bos taurus
-
-
1.14.13.32 microsome
-
Ovis aries
-
-

Organism

EC Number Organism UniProt Comment Textmining
1.14.13.32 Bos taurus
-
-
-
1.14.13.32 Ovis aries
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.13.32 liver
-
Bos taurus
-
1.14.13.32 liver
-
Ovis aries
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.13.32 albendazole + NADPH + O2
-
Bos taurus (+)-albendazole S-oxide + NADP+ 100% enantioselective towards the (+)-albendazole S-oxide ?
1.14.13.32 albendazole + NADPH + O2
-
Ovis aries (+)-albendazole S-oxide + NADP+ 100% enantioselective towards the (+)-albendazole S-oxide ?

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.13.32 flavin
-
Bos taurus
1.14.13.32 flavin
-
Ovis aries
1.14.13.32 NADPH
-
Bos taurus
1.14.13.32 NADPH
-
Ovis aries