Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Waters, S.B.; Devesa, V.; Fricke, M.W.; Creed, J.T.; Styblo, M.; Thomas, D.J.
    Glutathione modulates recombinant rat arsenic (+3 oxidation state) methyltransferase-catalyzed formation of trimethylarsine oxide and trimethylarsine (2004), Chem. Res. Toxicol., 17, 1621-1629.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.1.1.137 GSH stimulatory effect on the rate of methylarsonate and dimethylarsinate production from arsenite is concentration-dependent, suppression of formation of trimethylarsine oxide Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.1.1.137 GSH suppression of formation of trimethylarsine oxide, stimulatory effect on the rate of methylarsonate and dimethylarsinate production from arsenite is concentration-dependent Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.137 Rattus norvegicus Q8VHT6
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.137 S-adenosyl-L-methionine + arsenite
-
Rattus norvegicus S-adenosyl-L-homocysteine + methylarsonate
-
?
2.1.1.137 S-adenosyl-L-methionine + methylarsonite
-
Rattus norvegicus S-adenosyl-L-homocysteine + dimethylarsinate
-
?

Synonyms

EC Number Synonyms Comment Organism
2.1.1.137 arsenic (+3 oxidation state) methyltransferase
-
Rattus norvegicus
2.1.1.137 AS3MT
-
Rattus norvegicus