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Literature summary extracted from

  • Nakamura, N.; Katano, K.; Toba, S.; Kurosaka, A.
    Characterization of a novel polypeptide N-acetylgalactosaminyltransferase (dGalNAc-T3) from Drosophila (2004), Biol. Pharm. Bull., 27, 1509-1514.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.4.1.41 expression in COS7 cells Drosophila sp. (in: flies)

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.1.41 p-chloromercuriphenylsulfonic acid irreversible Drosophila sp. (in: flies)

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.1.41 0.0107
-
 UDP-N-acetyl-D-galactosamine pH 7.2, 25°C Drosophila sp. (in: flies)

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.4.1.41 Co2+ enhances activity with 60% of the activation observed with Mn2+ Drosophila sp. (in: flies)
2.4.1.41 Mn2+ most efficiently enhances activity among divalent cations tested Drosophila sp. (in: flies)
2.4.1.41 Ni2+ enhances activity with 20% of the activation observed with Mn2+ Drosophila sp. (in: flies)

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.41 Drosophila sp. (in: flies)
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.4.1.41 recombinant enzyme Drosophila sp. (in: flies)

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.41 larva
-
 Drosophila sp. (in: flies)
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.41 UDP-N-acetyl-D-galactosamine + AWIPTPPPIPG
-
 Drosophila sp. (in: flies) UDP + ?
-
 ?
2.4.1.41 UDP-N-acetyl-D-galactosamine + GTTPSPVPTTG
-
 Drosophila sp. (in: flies) UDP + ?
-
 ?
2.4.1.41 UDP-N-acetyl-D-galactosamine + ITTTTTPLPTG
-
 Drosophila sp. (in: flies) UDP + ?
-
 ?
2.4.1.41 UDP-N-acetyl-D-galactosamine + LPPVTTTPAPG
-
 Drosophila sp. (in: flies) UDP + ?
-
 ?
2.4.1.41 UDP-N-acetyl-D-galactosamine + MPTAGTPPPIG
-
 Drosophila sp. (in: flies) UDP + ?
-
 ?
2.4.1.41 UDP-N-acetyl-D-galactosamine + PADVTTAAPGG
-
 Drosophila sp. (in: flies) UDP + ?
-
 ?
2.4.1.41 UDP-N-acetyl-D-galactosamine + PGGDSSSYQPG
-
 Drosophila sp. (in: flies) UDP + ?
-
 ?
2.4.1.41 UDP-N-acetyl-D-galactosamine + PITTTTTVTPG
-
 Drosophila sp. (in: flies) UDP + ?
-
 ?
2.4.1.41 UDP-N-acetyl-D-galactosamine + polypeptide glycosylates peptides containing a sequence of XTPXP or TTAAP most efficiently Drosophila sp. (in: flies) UDP + N-acetyl-D-galactosaminyl-polypeptide
-
 ?
2.4.1.41 UDP-N-acetyl-D-galactosamine + PPAHGVTSAPG
-
 Drosophila sp. (in: flies) UDP + ?
-
 ?
2.4.1.41 UDP-N-acetyl-D-galactosamine + PPETTAAPPTG
-
 Drosophila sp. (in: flies) UDP + ?
-
 ?
2.4.1.41 UDP-N-acetyl-D-galactosamine + PPVVPFTPLPG
-
 Drosophila sp. (in: flies) UDP + ?
-
 ?
2.4.1.41 UDP-N-acetyl-D-galactosamine + PSPPITTTTTG
-
 Drosophila sp. (in: flies) UDP + ?
-
 ?
2.4.1.41 UDP-N-acetyl-D-galactosamine + PTTTPSPPITG
-
 Drosophila sp. (in: flies) UDP + ?
-
 ?
2.4.1.41 UDP-N-acetyl-D-galactosamine + SATTPAPPSSG preferred substrate Drosophila sp. (in: flies) UDP + ?
-
 ?
2.4.1.41 UDP-N-acetyl-D-galactosamine + SDAESSGPVPG
-
 Drosophila sp. (in: flies) UDP + ?
-
 ?
2.4.1.41 UDP-N-acetyl-D-galactosamine + SEVTTTLVPAG
-
 Drosophila sp. (in: flies) UDP + ?
-
 ?
2.4.1.41 UDP-N-acetyl-D-galactosamine + TSAPGTTPSPG
-
 Drosophila sp. (in: flies) UDP + ?
-
 ?
2.4.1.41 UDP-N-acetyl-D-galactosamine + TTAAPPTPSAG
-
 Drosophila sp. (in: flies) UDP + ?
-
 ?
2.4.1.41 UDP-N-acetyl-D-galactosamine + TTPLPTTTPSG
-
 Drosophila sp. (in: flies) UDP + ?
-
 ?
2.4.1.41 UDP-N-acetyl-D-galactosamine + TTSTTSAPGTG
-
 Drosophila sp. (in: flies) UDP + ?
-
 ?
2.4.1.41 UDP-N-acetyl-D-galactosamine + TTTTTTPKPTG
-
 Drosophila sp. (in: flies) UDP + ?
-
 ?
2.4.1.41 UDP-N-acetyl-D-galactosamine + TTTVTPTPTPG
-
 Drosophila sp. (in: flies) UDP + ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.4.1.41 dGalNAc-T3
-
 Drosophila sp. (in: flies)

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.4.1.41 29 33
-
 Drosophila sp. (in: flies)

Temperature Range [°C]

EC Number Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
2.4.1.41 17 37 17°C: about 40% of maximal activity, 37°C: about 65% of maximal activity Drosophila sp. (in: flies)

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.4.1.41 7.5 8.5
-
 Drosophila sp. (in: flies)

pH Range

EC Number pH Minimum pH Maximum Comment Organism
2.4.1.41 6.7 8.7 pH 6.7: about 30% of maximal activity, pH 8.7: about 40% of maximal activity Drosophila sp. (in: flies)

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.4.1.41 0.05
-
 p-chloromercuriphenylsulfonic acid pH 7.2, 25°C Drosophila sp. (in: flies)