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Literature summary extracted from

  • Vijayvergiya, C.; De Angelis, D.; Walther, M.; Kuhn, H.; Duvoisin, R.M.; Smith, D.H.; Wiedmann, M.
    High-level expression of rabbit 15-lipoxygenase induces collapse of the mitochondrial pH gradient in cell culture (2004), Biochemistry, 43, 15296-15302.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.13.11.33 additional information Oryctolagus cuniculus 15-lipoxygenase is capable of disrupting the pH gradient maintained by mitochondria in living cells without additional factors specific for red blood cell development. Ectopic expression of 15-lipoxygenase leads to the collaps of the mitochondrial pH gradient in nonerythroid cells ?
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 ?

Organism

EC Number Organism UniProt Comment Textmining
1.13.11.33 Oryctolagus cuniculus
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Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.13.11.33 reticulocyte
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 Oryctolagus cuniculus
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.13.11.33 arachidonic acid + O2
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 Oryctolagus cuniculus (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoic acid
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 ?
1.13.11.33 additional information 15-lipoxygenase is capable of disrupting the pH gradient maintained by mitochondria in living cells without additional factors specific for red blood cell development. Ectopic expression of 15-lipoxygenase leads to the collaps of the mitochondrial pH gradient in nonerythroid cells Oryctolagus cuniculus ?
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 ?

Synonyms

EC Number Synonyms Comment Organism
1.13.11.33 15-lipoxygenase
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 Oryctolagus cuniculus