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Literature summary extracted from

  • Senior, S.Z.; Mans, L.L.; VanGuilder, H.D.; Kelly, K.A.; Hendrich, M.P.; Elgren, T.E.
    Catecholase activity associated with copper-S100B (2003), Biochemistry, 42, 4392-4397.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.10.3.1 0.0000194
-
 L-noradrenaline pH 7.2, 20°C Bos taurus
1.10.3.1 0.0000239
-
 L-adrenaline pH 7.2, 20°C Bos taurus
1.10.3.1 0.000219
-
 D-Dopa pH 7.2, 20°C Bos taurus
1.10.3.1 0.000223
-
 L-Dopa pH 7.2, 20°C Bos taurus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.10.3.1 copper the copper centers in the protein are directly involved in the catechol oxidation Bos taurus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.10.3.1 additional information Bos taurus extremely low levels of activity suggest that this protein likely plays no direct metabolic role in the biodegradation of catecholamines ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.10.3.1 Bos taurus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.10.3.1
-
 Bos taurus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.10.3.1 brain
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.10.3.1 D-dopa + 1/2 O2
-
 Bos taurus D-dopaquinone + H2O
-
 ?
1.10.3.1 L-adrenaline + O2
-
 Bos taurus ?
-
 ?
1.10.3.1 L-dopa + 1/2 O2
-
 Bos taurus L-dopaquinone + H2O
-
 ?
1.10.3.1 L-noradrenaline + O2
-
 Bos taurus ?
-
 ?
1.10.3.1 additional information extremely low levels of activity suggest that this protein likely plays no direct metabolic role in the biodegradation of catecholamines Bos taurus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.10.3.1 copper-S100B
-
 Bos taurus

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
1.10.3.1 0.0000000912
-
 L-noradrenaline pH 7.2, 20°C Bos taurus
1.10.3.1 0.00000148
-
 L-adrenaline pH 7.2, 20°C Bos taurus
1.10.3.1 0.000338
-
 D-Dopa pH 7.2, 20°C Bos taurus
1.10.3.1 0.000459
-
 L-Dopa pH 7.2, 20°C Bos taurus