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Literature summary extracted from

  • Eubanks, L.M.; Poulter, C.D.
    Rhodobacter capsulatus 1-deoxy-D-xylulose 5-phosphate synthase: steady-state kinetics and substrate binding (2003), Biochemistry, 42, 1140-1149.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.2.1.7 2,3-diphospho-D-glyceric acid 0.1 mM, 50% inhibition Rhodobacter capsulatus
2.2.1.7 beta-fluoropyruvate dead-end inhibitor for pyruvate Rhodobacter capsulatus
2.2.1.7 beta-Glycerophosphate 0.3 mM, 40% inhibition Rhodobacter capsulatus
2.2.1.7 D-3-phosphoglyceric acid 0.16 mM, 23% inhibition Rhodobacter capsulatus
2.2.1.7 DL-alpha-glycerophosphate 0.29 mM, 50% inhibition Rhodobacter capsulatus
2.2.1.7 phosphonoacetohydroxamate 0.1 mM, 25% inhibition Rhodobacter capsulatus
2.2.1.7 phosphonopropionohydroxamate 0.1 mM, 10% inhibition Rhodobacter capsulatus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.2.1.7 0.068
-
 D-glyceraldehyde 3-phosphate pH 7.4, 37°C Rhodobacter capsulatus
2.2.1.7 0.44
-
 pyruvate pH 7.4, 37°C, cosubstrate: D-glyceraldehyde 3-phosphate Rhodobacter capsulatus
2.2.1.7 1.9
-
 pyruvate pH 7.4, 37°C, cosubstrate: D-glyceraldehyde Rhodobacter capsulatus
2.2.1.7 33
-
 D-glyceraldehyde pH 7.4, 37°C Rhodobacter capsulatus

Organism

EC Number Organism UniProt Comment Textmining
2.2.1.7 Rhodobacter capsulatus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.2.1.7 pyruvate + D-glyceraldehyde
-
 Rhodobacter capsulatus 1-deoxy-D-xylulose + CO2
-
 ?
2.2.1.7 pyruvate + D-glyceraldehyde 3-phosphate
-
 Rhodobacter capsulatus 1-deoxy-D-xylulose 5-phosphate + CO2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.2.1.7 DXP synthase
-
 Rhodobacter capsulatus

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
2.2.1.7 1.7
-
 D-glyceraldehyde pH 7.4, 37°C Rhodobacter capsulatus
2.2.1.7 1.7
-
 pyruvate pH 7.4, 37°C, cosubstrate: D-glyceraldehyde Rhodobacter capsulatus
2.2.1.7 1.9
-
 D-glyceraldehyde 3-phosphate pH 7.4, 37°C Rhodobacter capsulatus
2.2.1.7 1.9
-
 pyruvate pH 7.4, 37°C, cosubstrate: D-glyceraldehyde 3-phosphate Rhodobacter capsulatus