Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Fujiwara, S.; Yamanaka, A.; Hirooka, K.; Kobayashi, A.; Imanaka, T.; Fukusaki, E.
    Temperature-dependent modulation of farnesyl diphosphate/geranylgeranyl diphosphate synthase from hyperthermophilic archaea (2004), Biochem. Biophys. Res. Commun., 325, 1066-1074.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.5.1.29 expression in Escherichia coli Thermococcus kodakarensis

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.5.1.29 0.0017
-
 farnesyl diphosphate pH 8.0, 70°C Thermococcus kodakarensis
2.5.1.29 0.0022
-
 geranyl diphosphate pH 8.0, 70°C Thermococcus kodakarensis
2.5.1.29 0.0094
-
 farnesyl diphosphate pH 8.0, 90°C Thermococcus kodakarensis
2.5.1.29 0.0095
-
 dimethylallyl diphosphate pH 8.0, 70°C Thermococcus kodakarensis
2.5.1.29 0.022
-
 geranyl diphosphate pH 8.0, 90°C Thermococcus kodakarensis
2.5.1.29 0.023
-
 dimethylallyl diphosphate pH 8.0, 90°C Thermococcus kodakarensis

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.5.1.29 38326
-
 2 * 38326, calculation from nucleotide sequence Thermococcus kodakarensis
2.5.1.29 85000
-
 gel filtration Thermococcus kodakarensis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.5.1.29 (E,E)-farnesyl diphosphate + isopentenyl diphosphate Thermococcus kodakarensis bifunctional enzyme EC2.5.1.29/EC2.5.1.10, the FPP/GGPP product ratio increases with the rise of the reaction temperature. The enzyme contributes to adjust the membrane composition to the cell growth temperature modulating its substrate and product specificities geranylgeranyl diphosphate + diphosphate
-
 ?
2.5.1.29 geranyl diphosphate + isopentenyl diphosphate Thermococcus kodakarensis bifunctional enzyme EC2.5.1.29/EC2.5.1.10, the FPP/GGPP product ratio increases with the rise of the reaction temperature. The enzyme contributes to adjust the membrane composition to the cell growth temperature modulating its substrate and product specificities diphosphate + trans,trans-farnesyl diphosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.5.1.29 Thermococcus kodakarensis Q76CZ2
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.5.1.29
-
 Thermococcus kodakarensis

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.5.1.29 (E,E)-farnesyl diphosphate + isopentenyl diphosphate bifunctional enzyme EC2.5.1.29/EC2.5.1.10, the FPP/GGPP product ratio increases with the rise of the reaction temperature. The enzyme contributes to adjust the membrane composition to the cell growth temperature modulating its substrate and product specificities Thermococcus kodakarensis geranylgeranyl diphosphate + diphosphate
-
 ?
2.5.1.29 (E,E)-farnesyl diphosphate + isopentenyl diphosphate bifunctional enzyme EC2.5.1.29/EC2.5.1.10, the FPP/GGPP product ratio increases with the rise of the reaction temperature Thermococcus kodakarensis geranylgeranyl diphosphate + diphosphate
-
 ?
2.5.1.29 dimethylallyl diphosphate + isopentenyl diphosphate bifunctional enzyme EC2.5.1.29/EC2.5.1.10, the FPP/GGPP product ratio increases with the rise of the reaction temperature Thermococcus kodakarensis ? + diphosphate
-
 ?
2.5.1.29 geranyl diphosphate + isopentenyl diphosphate bifunctional enzyme EC2.5.1.29/EC2.5.1.10, the FPP/GGPP product ratio increases with the rise of the reaction temperature. The enzyme contributes to adjust the membrane composition to the cell growth temperature modulating its substrate and product specificities Thermococcus kodakarensis diphosphate + trans,trans-farnesyl diphosphate
-
 ?
2.5.1.29 geranyl diphosphate + isopentenyl diphosphate bifunctional enzyme EC2.5.1.29/EC2.5.1.10, the FPP/GGPP product ratio increases with the rise of the reaction temperature Thermococcus kodakarensis diphosphate + trans,trans-farnesyl diphosphate
-
 ?

Subunits

EC Number Subunits Comment Organism
2.5.1.29 dimer 2 * 38326, calculation from nucleotide sequence Thermococcus kodakarensis

Synonyms

EC Number Synonyms Comment Organism
2.5.1.29 farnesyl diphosphate/geranylgeranyl diphosphate synthase bifunctional enzyme EC2.5.1.29/EC2.5.1.10 Thermococcus kodakarensis
2.5.1.29 Tk-IdsA
-
 Thermococcus kodakarensis
2.5.1.29 trans-prenyl diphosphate synthase
-
 Thermococcus kodakarensis