EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
2.4.1.34 | CaCl2 | 7 mM, 2fold increase in activity | Cryptococcus neoformans | |
2.4.1.34 | EDTA | maximal activity at 50 mM | Cryptococcus neoformans | |
2.4.1.34 | MgCl2 | 5 mM, 3fold increase in activity | Cryptococcus neoformans |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.4.1.34 | caspofungin | 50% inhibition at 0.00013 mg/ml | Aspergillus fumigatus | |
2.4.1.34 | caspofungin | 50% inhibition at 0.016 mg/ml | Cryptococcus neoformans | |
2.4.1.34 | caspofungin | 50% inhibition at 0.004 mg/ml | Neurospora crassa | |
2.4.1.34 | caspofungin | 50% inhibition at 0.00013 mg/ml | Saccharomyces cerevisiae | |
2.4.1.34 | cilofungin | 50% inhibition at 0.064 mg/ml | Cryptococcus neoformans |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.4.1.34 | additional information | - |
additional information | optimization of in vitro assay conditions | Cryptococcus neoformans | |
2.4.1.34 | 0.21 | - |
UDP-glucose | pH 7.75 | Cryptococcus neoformans |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.4.1.34 | Aspergillus fumigatus | - |
- |
- |
2.4.1.34 | Cryptococcus neoformans | - |
- |
- |
2.4.1.34 | Neurospora crassa | - |
- |
- |
2.4.1.34 | Saccharomyces cerevisiae | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.1.34 | UDP-glucose + (1,3-beta-D-glucosyl)n | - |
Saccharomyces cerevisiae | UDP + (1,3-beta-D-glucosyl)n+1 | - |
? | |
2.4.1.34 | UDP-glucose + (1,3-beta-D-glucosyl)n | - |
Neurospora crassa | UDP + (1,3-beta-D-glucosyl)n+1 | - |
? | |
2.4.1.34 | UDP-glucose + (1,3-beta-D-glucosyl)n | - |
Cryptococcus neoformans | UDP + (1,3-beta-D-glucosyl)n+1 | - |
? | |
2.4.1.34 | UDP-glucose + (1,3-beta-D-glucosyl)n | - |
Aspergillus fumigatus | UDP + (1,3-beta-D-glucosyl)n+1 | - |
? |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
2.4.1.34 | 7.75 | - |
- |
Cryptococcus neoformans |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.4.1.34 | 0.00017 | - |
caspofungin | pH 7.75, 25°C | Cryptococcus neoformans | |
2.4.1.34 | 0.00067 | - |
caspofungin | pH 7.75, 25°C | Saccharomyces cerevisiae | |
2.4.1.34 | 0.0022 | - |
caspofungin | pH 7.75, 25°C | Neurospora crassa | |
2.4.1.34 | 0.0041 | - |
caspofungin | pH 7.75, 25°C | Aspergillus fumigatus | |
2.4.1.34 | 0.022 | - |
cilofungin | pH 7.75, 25°C | Cryptococcus neoformans |