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Literature summary extracted from

  • Yankovskaya, V.; Horsefield, R.; Tornroth, S.; Luna-Chavez, C.; Miyoshi, H.; Leger, C.; Byrne, B.; Cecchini, G.; Iwata, S.
    Architecture of succinate dehydrogenase and reactive oxygen species generation (2003), Science, 299, 700-704.
    View publication on PubMed

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
1.3.5.1 structure of SQR at 2.6 A resolution Escherichia coli
1.3.5.1 structure of SQR is reported at 2.6 A resolution. The SQR redox centers are arranged in a manner that aids the prevention of reactive oxygen species formation at the flavin adenine dinucleotide. This is likely to be the main reason SQR is expressed during aerobic respiration rather than the related enzyme fumarate reductase, which produces high levels of reactive oxygen species Escherichia coli

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.3.5.1 120000
-
3 * 120000 Da, SQR is packed as a trimer, determined by crystal structure analysis Escherichia coli
1.3.5.1 360000
-
trimer Escherichia coli

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.3.5.1 succinate + ubiquinone Escherichia coli
-
fumarate + ubiquinol
-
?

Organism

EC Number Organism UniProt Comment Textmining
1.3.5.1 Escherichia coli
-
-
-
1.3.5.1 Escherichia coli P0AC41
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.5.1 succinate + ubiquinone
-
Escherichia coli fumarate + ubiquinol
-
?

Subunits

EC Number Subunits Comment Organism
1.3.5.1 trimer 3 * 120000 Da, SQR is packed as a trimer, determined by crystal structure analysis Escherichia coli

Synonyms

EC Number Synonyms Comment Organism
1.3.5.1 SQR
-
Escherichia coli
1.3.5.1 succinate dehydrogenase
-
Escherichia coli

Cofactor

EC Number Cofactor Comment Organism Structure
1.3.5.1 FAD
-
Escherichia coli