Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • de Vries, R.P.; Flitter, S.J.; van de Vondervoort, P.J.; Chaveroche, M.K.; Fontaine, T.; Fillinger, S.; Ruijter, G.J.; d'Enfert, C.; Visser, J.
    Glycerol dehydrogenase, encoded by gldB is essential for osmotolerance in Aspergillus nidulans (2003), Mol. Microbiol., 49, 131-141.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.1.1.72 NaCl The presence of 1 M NaCl results in a significant increase in activity in the wild-type strain. Aspergillus nidulans

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.1.1.72 the gene gldB Aspergillus nidulans

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.1.1.72 36980
-
 calculated from amino acid sequence Aspergillus nidulans

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.72 glycerol + NADP+ Aspergillus nidulans The enzyme plays a role in the glycerol biosynthesis during growth and in osmotolerance. The glycerol biosynthesis by enzyme is required for germination at high osmolarity. dihydroxyacetone + NADPH + H+
-
 r

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.72 Aspergillus nidulans Q7Z8L1
-
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.1.1.72 additional information
-
 comparison of activity in the wild-type and two gldB disruption strains. The presence of 1 M NaCl results in a significant increase in activity in the wild-type strain. In the gldB disruptions hardly any activity is detected. Aspergillus nidulans

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.72 glycerol + NADP+
-
 Aspergillus nidulans dihydroxyacetone + NADPH + H+
-
 r
1.1.1.72 glycerol + NADP+ The enzyme plays a role in the glycerol biosynthesis during growth and in osmotolerance. The glycerol biosynthesis by enzyme is required for germination at high osmolarity. Aspergillus nidulans dihydroxyacetone + NADPH + H+
-
 r

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.72 NADP+
-
 Aspergillus nidulans
1.1.1.72 NADPH
-
 Aspergillus nidulans

pI Value

EC Number Organism Comment pI Value Maximum pI Value
1.1.1.72 Aspergillus nidulans
-
-
 6