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Literature summary extracted from

  • Markova, N.G.; Pinkas-Sarafova, A.; Karaman-Jurukovska, N.; Jurukovski, V.; Simon, M.
    Expression pattern and biochemical characteristics of a major epidermal retinol dehydrogenase (2003), Mol. Genet. Metab., 78, 119-135.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.300 (3beta)-3-[(3-carboxypropanoyl)oxy]-11-oxoolean-12-en-30-oic acid 0.5 mM, 60% of inhibition Homo sapiens
1.1.1.300 additional information not inhibitory: methylpyrazole, phenylmethylsulfonylfluoride Homo sapiens
1.1.1.300 Phenylarsine oxide 1 mM, 85% of inhibition Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.1.1.300 microsome
-
 Homo sapiens
-
-

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.300 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.300 carcinoma cell squamos cell carcinoma, SCC tumor Homo sapiens
-
1.1.1.300 skin and foreskin Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.300 additional information prefers NADP+ over NAD+ Homo sapiens ?
-
 ?
1.1.1.300 retinol + NAD+
-
 Homo sapiens retinal + NADH
-
 ?
1.1.1.300 retinol + NADP+
-
 Homo sapiens retinal + NADPH
-
 ?
1.1.1.300 retinol bound to cellular retinol binding protein + NADP+
-
 Homo sapiens retinal bound to cellular retinol binding protein + NADPH
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.1.1.300 hRoDH
-
 Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.300 NAD+
-
 Homo sapiens
1.1.1.300 NADP+
-
 Homo sapiens