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Literature summary extracted from

  • Egashira, T.; Takayama, F.; Sakai, K.
    Inhibition by Zn2+ of A-form monoamine oxidase in monkey brain mitochondria (2003), J. Pharm. Sci., 91, 239-245.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.4.3.4 CdSO4 1 mM, 10% inhibition, monoamine oxidase B; 1 mM, 90% inhibition with serotonin as substrate, monoamine oxidase A Macaca fuscata
1.4.3.4 CuSO4 1 mM, 95% inhibition with serotonin as substrate, monoamine oxidase A Macaca fuscata
1.4.3.4 ZnSO4 1 mM, 10% inhibition, monoamine oxidase B; 1 mM, 85% inhibition with serotonin as substrate, competitive, reversible, monoamine oxidase A Macaca fuscata
1.4.3.4 ZnSO4 1 mM, about 20% inhibition, monoamine oxidase A Oryctolagus cuniculus
1.4.3.4 ZnSO4 1 mM, about 20% inhibition, monoamine oxidase A Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.4.3.4 mitochondrion
-
 Rattus norvegicus 5739
-
1.4.3.4 mitochondrion
-
 Oryctolagus cuniculus 5739
-
1.4.3.4 mitochondrion
-
 Macaca fuscata 5739
-

Organism

EC Number Organism UniProt Comment Textmining
1.4.3.4 Macaca fuscata
-
-
-
1.4.3.4 Oryctolagus cuniculus
-
-
-
1.4.3.4 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.4.3.4 brain
-
 Rattus norvegicus
-
1.4.3.4 brain
-
 Oryctolagus cuniculus
-
1.4.3.4 brain
-
 Macaca fuscata
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.4.3.4 2-phenylethylamine + H2O + O2
-
 Rattus norvegicus 2-phenylethanal + NH3 + H2O2
-
 ?
1.4.3.4 2-phenylethylamine + H2O + O2
-
 Oryctolagus cuniculus 2-phenylethanal + NH3 + H2O2
-
 ?
1.4.3.4 2-phenylethylamine + H2O + O2
-
 Macaca fuscata 2-phenylethanal + NH3 + H2O2
-
 ?
1.4.3.4 serotonin + H2O + O2
-
 Rattus norvegicus (5-hydroxy-1H-indol-3-yl)acetaldehyde + NH3 + H2O2
-
 ?
1.4.3.4 serotonin + H2O + O2
-
 Oryctolagus cuniculus (5-hydroxy-1H-indol-3-yl)acetaldehyde + NH3 + H2O2
-
 ?
1.4.3.4 serotonin + H2O + O2
-
 Macaca fuscata (5-hydroxy-1H-indol-3-yl)acetaldehyde + NH3 + H2O2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.4.3.4 MAO-A
-
 Rattus norvegicus
1.4.3.4 MAO-A
-
 Oryctolagus cuniculus
1.4.3.4 MAO-A
-
 Macaca fuscata
1.4.3.4 MAO-B
-
 Macaca fuscata
1.4.3.4 monoamine oxidase A
-
 Rattus norvegicus
1.4.3.4 monoamine oxidase A
-
 Oryctolagus cuniculus
1.4.3.4 monoamine oxidase A
-
 Macaca fuscata
1.4.3.4 monoamine oxidase B
-
 Macaca fuscata

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
1.4.3.4 0.00049
-
 ZnSO4 monoamine oxidase A Macaca fuscata